Stricture occurring after endoscopic submucosal dissection for esophageal and gastric tumors

Korean ESD Study Group

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Endoscopic sub mucosal dissection (ESD) is a widely accepted treatment for early gastric and esophageal cancer. Compared to endoscopic mucosal resection, ESD has the advantage of enabling en bloc removal of tumors regardless of their size. However, ESD can result in a large artificial ulcer, which may lead to a considerable deformity. Circumferential mucosal defects of more than three-fourths the esophageal circumference, long longitudinal mucosal defects (>30 mm), and lesions in the upper esophagus are significant risk factors for the development of post-ESD strictures of the esophagus. In the stomach, a circumferential mucosal defects more than three-fourths in extent and longitudinal mucosal defects >5 cm are risk factors of post-ESD stricture. If scheduled early, regular endoscopic balloon dilation is effective in controlling and preventing post-ESD stricture. Moreover, intralesional steroid injections or oral steroids can achieve remission of dysphagia or reduce the need for repeated endoscopic balloon dilation. However, further study is needed to improve the prevention of stricture formation.

Original languageEnglish
Pages (from-to)516-522
Number of pages7
JournalClinical Endoscopy
Volume47
Issue number6
DOIs
Publication statusPublished - 2014 Jan 1

Fingerprint

Dissection
Stomach
Pathologic Constriction
Neoplasms
Esophagus
Dilatation
Steroids
Intralesional Injections
Esophageal Neoplasms
Deglutition Disorders
Ulcer
Stomach Neoplasms
Endoscopic Mucosal Resection
Therapeutics

Keywords

  • Endoscopic submucosal dissection
  • Esophagus
  • Stomach
  • Stricture

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Radiology Nuclear Medicine and imaging
  • Gastroenterology

Cite this

Stricture occurring after endoscopic submucosal dissection for esophageal and gastric tumors. / Korean ESD Study Group.

In: Clinical Endoscopy, Vol. 47, No. 6, 01.01.2014, p. 516-522.

Research output: Contribution to journalArticle

@article{5aa46103f5cf43d29ff8a62a858ec51b,
title = "Stricture occurring after endoscopic submucosal dissection for esophageal and gastric tumors",
abstract = "Endoscopic sub mucosal dissection (ESD) is a widely accepted treatment for early gastric and esophageal cancer. Compared to endoscopic mucosal resection, ESD has the advantage of enabling en bloc removal of tumors regardless of their size. However, ESD can result in a large artificial ulcer, which may lead to a considerable deformity. Circumferential mucosal defects of more than three-fourths the esophageal circumference, long longitudinal mucosal defects (>30 mm), and lesions in the upper esophagus are significant risk factors for the development of post-ESD strictures of the esophagus. In the stomach, a circumferential mucosal defects more than three-fourths in extent and longitudinal mucosal defects >5 cm are risk factors of post-ESD stricture. If scheduled early, regular endoscopic balloon dilation is effective in controlling and preventing post-ESD stricture. Moreover, intralesional steroid injections or oral steroids can achieve remission of dysphagia or reduce the need for repeated endoscopic balloon dilation. However, further study is needed to improve the prevention of stricture formation.",
keywords = "Endoscopic submucosal dissection, Esophagus, Stomach, Stricture",
author = "{Korean ESD Study Group} and {Ha Kim}, Gwang and Jee, {Sam Ryong} and Jang, {Jae Young} and Shin, {Sung Kwan} and Choi, {Kee Don} and Lee, {Jun Haeng} and Kim, {Sang Gyun} and Sung, {Jae Kyu} and Choi, {Suck Chei} and Jeon, {Seong Woo} and Jang, {Byung Ik} and Huh, {Kyu Chan} and Chang, {Dong Kyung} and Jung, {Sung Ae} and Bora Keum and Cho, {Jin Woong} and Choi, {Il Ju} and Jung, {Hwoon Yong}",
year = "2014",
month = "1",
day = "1",
doi = "10.5946/ce.2014.47.6.516",
language = "English",
volume = "47",
pages = "516--522",
journal = "Clinical Endoscopy",
issn = "2234-2400",
publisher = "Korean Society of Gastrointestinal Endoscopy",
number = "6",

}

TY - JOUR

T1 - Stricture occurring after endoscopic submucosal dissection for esophageal and gastric tumors

AU - Korean ESD Study Group

AU - Ha Kim, Gwang

AU - Jee, Sam Ryong

AU - Jang, Jae Young

AU - Shin, Sung Kwan

AU - Choi, Kee Don

AU - Lee, Jun Haeng

AU - Kim, Sang Gyun

AU - Sung, Jae Kyu

AU - Choi, Suck Chei

AU - Jeon, Seong Woo

AU - Jang, Byung Ik

AU - Huh, Kyu Chan

AU - Chang, Dong Kyung

AU - Jung, Sung Ae

AU - Keum, Bora

AU - Cho, Jin Woong

AU - Choi, Il Ju

AU - Jung, Hwoon Yong

PY - 2014/1/1

Y1 - 2014/1/1

N2 - Endoscopic sub mucosal dissection (ESD) is a widely accepted treatment for early gastric and esophageal cancer. Compared to endoscopic mucosal resection, ESD has the advantage of enabling en bloc removal of tumors regardless of their size. However, ESD can result in a large artificial ulcer, which may lead to a considerable deformity. Circumferential mucosal defects of more than three-fourths the esophageal circumference, long longitudinal mucosal defects (>30 mm), and lesions in the upper esophagus are significant risk factors for the development of post-ESD strictures of the esophagus. In the stomach, a circumferential mucosal defects more than three-fourths in extent and longitudinal mucosal defects >5 cm are risk factors of post-ESD stricture. If scheduled early, regular endoscopic balloon dilation is effective in controlling and preventing post-ESD stricture. Moreover, intralesional steroid injections or oral steroids can achieve remission of dysphagia or reduce the need for repeated endoscopic balloon dilation. However, further study is needed to improve the prevention of stricture formation.

AB - Endoscopic sub mucosal dissection (ESD) is a widely accepted treatment for early gastric and esophageal cancer. Compared to endoscopic mucosal resection, ESD has the advantage of enabling en bloc removal of tumors regardless of their size. However, ESD can result in a large artificial ulcer, which may lead to a considerable deformity. Circumferential mucosal defects of more than three-fourths the esophageal circumference, long longitudinal mucosal defects (>30 mm), and lesions in the upper esophagus are significant risk factors for the development of post-ESD strictures of the esophagus. In the stomach, a circumferential mucosal defects more than three-fourths in extent and longitudinal mucosal defects >5 cm are risk factors of post-ESD stricture. If scheduled early, regular endoscopic balloon dilation is effective in controlling and preventing post-ESD stricture. Moreover, intralesional steroid injections or oral steroids can achieve remission of dysphagia or reduce the need for repeated endoscopic balloon dilation. However, further study is needed to improve the prevention of stricture formation.

KW - Endoscopic submucosal dissection

KW - Esophagus

KW - Stomach

KW - Stricture

UR - http://www.scopus.com/inward/record.url?scp=84912109742&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84912109742&partnerID=8YFLogxK

U2 - 10.5946/ce.2014.47.6.516

DO - 10.5946/ce.2014.47.6.516

M3 - Article

VL - 47

SP - 516

EP - 522

JO - Clinical Endoscopy

JF - Clinical Endoscopy

SN - 2234-2400

IS - 6

ER -