Studies of advanced lignin valorization based on various types of lignolytic enzymes and microbes

Sang Kyu Shin; Young Jin Ko; Jeong Eun Hyeon; Sung Ok Han

doi:10.1016/j.biortech.2019.121728

Studies of advanced lignin valorization based on various types of lignolytic enzymes and microbes

Sang Kyu Shin, Young Jin Ko, Jeong Eun Hyeon, Sung Ok Han

Department of Biotechnology

Research output: Contribution to journal › Review article › peer-review

17 Citations (Scopus)

Abstract

Lignin is a robust material that is considered useless because it has an inhibitory effect on microbes and acts as a physical barrier for cellulose degradation. Therefore, it has been removed from cellulosic biomass to produce high-value materials. However, lignin monomers can be converted to value-added chemicals such as biodegradable plastics and food additives by appropriately engineered microbes. Lignin degradation through peroxidase, laccase and other proteins with auxiliary activity is the first step in lignin valorization. Metabolic engineering of microorganisms for increased tolerance and production yield is the second step for lignin valorization. Here, this review offers a summary of current biotechnologies using various enzymatic activities, synergistic enzyme mixtures and metabolic engineering for lignin valorization in biorefinery.

Original language	English
Article number	121728
Journal	Bioresource technology
Volume	289
DOIs	https://doi.org/10.1016/j.biortech.2019.121728
Publication status	Published - 2019 Oct

Keywords

Biorefinery
Lignin valorization
Lignolytic enzyme mixture
Metabolic engineering

ASJC Scopus subject areas

Bioengineering
Environmental Engineering
Renewable Energy, Sustainability and the Environment
Waste Management and Disposal

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.biortech.2019.121728

Cite this

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title = "Studies of advanced lignin valorization based on various types of lignolytic enzymes and microbes",

abstract = "Lignin is a robust material that is considered useless because it has an inhibitory effect on microbes and acts as a physical barrier for cellulose degradation. Therefore, it has been removed from cellulosic biomass to produce high-value materials. However, lignin monomers can be converted to value-added chemicals such as biodegradable plastics and food additives by appropriately engineered microbes. Lignin degradation through peroxidase, laccase and other proteins with auxiliary activity is the first step in lignin valorization. Metabolic engineering of microorganisms for increased tolerance and production yield is the second step for lignin valorization. Here, this review offers a summary of current biotechnologies using various enzymatic activities, synergistic enzyme mixtures and metabolic engineering for lignin valorization in biorefinery.",

keywords = "Biorefinery, Lignin valorization, Lignolytic enzyme mixture, Metabolic engineering",

author = "Shin, {Sang Kyu} and Ko, {Young Jin} and Hyeon, {Jeong Eun} and Han, {Sung Ok}",

note = "Funding Information: This work was supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIP) (No. 2018R1A2B2003704) and Korea University Grant. Funding Information: This work was supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government ( MSIP ) (No. 2018R1A2B2003704 ) and Korea University Grant. Publisher Copyright: {\textcopyright} 2019 Elsevier Ltd",

year = "2019",

month = oct,

doi = "10.1016/j.biortech.2019.121728",

language = "English",

volume = "289",

journal = "Bioresource Technology",

issn = "0960-8524",

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T1 - Studies of advanced lignin valorization based on various types of lignolytic enzymes and microbes

AU - Shin, Sang Kyu

AU - Ko, Young Jin

AU - Hyeon, Jeong Eun

AU - Han, Sung Ok

N1 - Funding Information: This work was supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIP) (No. 2018R1A2B2003704) and Korea University Grant. Funding Information: This work was supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government ( MSIP ) (No. 2018R1A2B2003704 ) and Korea University Grant. Publisher Copyright: © 2019 Elsevier Ltd

PY - 2019/10

Y1 - 2019/10

N2 - Lignin is a robust material that is considered useless because it has an inhibitory effect on microbes and acts as a physical barrier for cellulose degradation. Therefore, it has been removed from cellulosic biomass to produce high-value materials. However, lignin monomers can be converted to value-added chemicals such as biodegradable plastics and food additives by appropriately engineered microbes. Lignin degradation through peroxidase, laccase and other proteins with auxiliary activity is the first step in lignin valorization. Metabolic engineering of microorganisms for increased tolerance and production yield is the second step for lignin valorization. Here, this review offers a summary of current biotechnologies using various enzymatic activities, synergistic enzyme mixtures and metabolic engineering for lignin valorization in biorefinery.

AB - Lignin is a robust material that is considered useless because it has an inhibitory effect on microbes and acts as a physical barrier for cellulose degradation. Therefore, it has been removed from cellulosic biomass to produce high-value materials. However, lignin monomers can be converted to value-added chemicals such as biodegradable plastics and food additives by appropriately engineered microbes. Lignin degradation through peroxidase, laccase and other proteins with auxiliary activity is the first step in lignin valorization. Metabolic engineering of microorganisms for increased tolerance and production yield is the second step for lignin valorization. Here, this review offers a summary of current biotechnologies using various enzymatic activities, synergistic enzyme mixtures and metabolic engineering for lignin valorization in biorefinery.

KW - Biorefinery

KW - Lignin valorization

KW - Lignolytic enzyme mixture

KW - Metabolic engineering

UR - http://www.scopus.com/inward/record.url?scp=85068211315&partnerID=8YFLogxK

U2 - 10.1016/j.biortech.2019.121728

DO - 10.1016/j.biortech.2019.121728

M3 - Review article

C2 - 31277889

AN - SCOPUS:85068211315

VL - 289

JO - Bioresource Technology

JF - Bioresource Technology

SN - 0960-8524

M1 - 121728

ER -

Studies of advanced lignin valorization based on various types of lignolytic enzymes and microbes

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

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