Sub-100 nm gold nanohole-enhanced Raman scattering on flexible PDMS sheets

Seunghyun Lee, Andry Ongko, Ho Young Kim, Sang Gu Yim, Geumhye Jeon, Hee Jin Jeong, Seungwoo Lee, Minseok Kwak, Seung Yun Yang

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Surface-enhanced Raman spectroscopy (SERS) is a highly sensitive vibrational spectroscopy technique enabling detection of multiple analytes at the molecular level in a nondestructive and rapid manner. In this work, we introduce a new approach to fabricate deep subwavelength-scaled (sub-100 nm) metallic nanohole arrays (quasi-3D metallic nanoholes) on flexible and highly efficient SERS substrates. Target structures have been fabricated using a two-step process consisting of (i) direct pattern transfer of spin-coated polymer films onto polydimethylsiloxane (PDMS) substrates by plasma etching with transferred anodic aluminum oxide masks, and (ii) producing SERS-active substrates by functionalization of the etched polymeric films followed by Au deposition. Such an all-dry, top-down lithographic approach enables on-demand patterning of SERS-active metallic nanoholes with high structural fidelity even onto flexible and stretchable substrates, thus making possible multiple sensing modes in a versatile fashion. For example, metallic nanoholes on flexible PDMS substrates are highly amenable to their integration with curved glass sticks, which can be used in optical fiber-integrated SERS systems. Au surfaces immobilized by probe DNA molecules show a selective enhancement of Raman scattering with Cy5-labeled complementary DNA (as compared to flat Au surfaces), demonstrating the potential of using the quasi-3D Au nanohole arrays for bio-sensing applications.

Original languageEnglish
Article number315301
JournalNanotechnology
Volume27
Issue number31
DOIs
Publication statusPublished - 2016 Jun 23
Externally publishedYes

Fingerprint

Raman Spectrum Analysis
Polydimethylsiloxane
Gold
Raman scattering
Raman spectroscopy
Substrates
Polymer films
Immobilized Nucleic Acids
DNA
Optical Fibers
Aluminum Oxide
Vibrational spectroscopy
Masks
Plasma etching
DNA Probes
Glass
baysilon
Spectrum Analysis
Polymers
Complementary DNA

Keywords

  • AAO mask
  • DNA detection
  • flexible SERS substrate
  • gold nanoholes array

ASJC Scopus subject areas

  • Bioengineering
  • Chemistry(all)
  • Materials Science(all)
  • Mechanics of Materials
  • Mechanical Engineering
  • Electrical and Electronic Engineering

Cite this

Lee, S., Ongko, A., Kim, H. Y., Yim, S. G., Jeon, G., Jeong, H. J., ... Yang, S. Y. (2016). Sub-100 nm gold nanohole-enhanced Raman scattering on flexible PDMS sheets. Nanotechnology, 27(31), [315301]. https://doi.org/10.1088/0957-4484/27/31/315301

Sub-100 nm gold nanohole-enhanced Raman scattering on flexible PDMS sheets. / Lee, Seunghyun; Ongko, Andry; Kim, Ho Young; Yim, Sang Gu; Jeon, Geumhye; Jeong, Hee Jin; Lee, Seungwoo; Kwak, Minseok; Yang, Seung Yun.

In: Nanotechnology, Vol. 27, No. 31, 315301, 23.06.2016.

Research output: Contribution to journalArticle

Lee, S, Ongko, A, Kim, HY, Yim, SG, Jeon, G, Jeong, HJ, Lee, S, Kwak, M & Yang, SY 2016, 'Sub-100 nm gold nanohole-enhanced Raman scattering on flexible PDMS sheets', Nanotechnology, vol. 27, no. 31, 315301. https://doi.org/10.1088/0957-4484/27/31/315301
Lee, Seunghyun ; Ongko, Andry ; Kim, Ho Young ; Yim, Sang Gu ; Jeon, Geumhye ; Jeong, Hee Jin ; Lee, Seungwoo ; Kwak, Minseok ; Yang, Seung Yun. / Sub-100 nm gold nanohole-enhanced Raman scattering on flexible PDMS sheets. In: Nanotechnology. 2016 ; Vol. 27, No. 31.
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