Successful extracorporeal life support after potentially fatal pulmonary oedema caused by inhalation of nitric and hydrofluoric acid fumes

Jae Seung Shin, Sung Woo Lee, Nak Hoon Kim, Jon Su Park, Kwang Ja Kim, Sung Hyuk Choi, Yun Sik Hong

Research output: Contribution to journalArticle

5 Citations (Scopus)


Two patients presented with potentially fatal pulmonary oedema after accidental exposure to nitric and hydrofluoric acid fumes during electroplating. Despite aggressive respiratory support, one succumbed to respiratory failure 3.5 h after inhalation. The other patient also rapidly progressed to respiratory failure. Extracorporeal life support (ECLS) was started 5 h after exposure at the ED. During ECLS, hypoxia improved, but pulmonary oedema shown by chest radiography became aggravated. N-Acetyl cysteine and calcium gluconate were given i.v. on the first day of admission and nebulised for 48 h after exposure. Pulmonary secretions were significantly reduced 24 h after the nebulising therapy began. Ultimately, the patient was discharged without serious pulmonary or neurological complications after 28 days of hospitalisation. In this case, early ECLS, nebulised antioxidant and antidote were available to treat potentially fatal pulmonary oedema after exposure to nitric and hydrofluoric acid fumes.

Original languageEnglish
Pages (from-to)184-188
Number of pages5
Issue number1
Publication statusPublished - 2007 Oct 1



  • Calcium gluconate
  • Extracorporeal life support
  • Hydrofluoric acid
  • N-Acetylcysteine
  • Nitric acid
  • Pulmonary oedema

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Nursing(all)

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