Sudden Atelectasis and respiratory failure in a neutropenic patient: Atypical presentation of pseudomembranous necrotizing bronchial aspergillosis

Ji Yun Noh, Seok Jin Kim, Eun Hae Kang, Bo Kyoung Seo, Kyoung Ho Rho, Yang Seok Chae, Byung Soo Kim

Research output: Contribution to journalArticle

Abstract

Pseudomembranous necrotizing bronchial aspergillosis (PNBA) is a rare form of invasive aspergillosis with a very poor prognosis. The symptoms are non-specific, and the necrotizing plugs cause airway obstruction. Atelectasis and respiratory failure can be the initial manifestations. Recently, we treated an immunocompromised patient with PNBA, who presented with a sudden onset of atelectasis and acute respiratory failure. There were no preceding signs except for a mild cough and one febrile episode. Bronchoscopy revealed PNBA, and Aspergillus nidulans was cultured from the bronchial wash.

Original languageEnglish
Pages (from-to)463-466
Number of pages4
JournalKorean Journal of Internal Medicine
Volume27
Issue number4
DOIs
Publication statusPublished - 2012 Dec 1

Fingerprint

Aspergillosis
Pulmonary Atelectasis
Respiratory Insufficiency
Aspergillus nidulans
Immunocompromised Host
Bronchoscopy
Airway Obstruction
Cough
Fever

Keywords

  • Aspergillosis
  • Neutropenia
  • Pneumonia

ASJC Scopus subject areas

  • Internal Medicine

Cite this

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abstract = "Pseudomembranous necrotizing bronchial aspergillosis (PNBA) is a rare form of invasive aspergillosis with a very poor prognosis. The symptoms are non-specific, and the necrotizing plugs cause airway obstruction. Atelectasis and respiratory failure can be the initial manifestations. Recently, we treated an immunocompromised patient with PNBA, who presented with a sudden onset of atelectasis and acute respiratory failure. There were no preceding signs except for a mild cough and one febrile episode. Bronchoscopy revealed PNBA, and Aspergillus nidulans was cultured from the bronchial wash.",
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T2 - Atypical presentation of pseudomembranous necrotizing bronchial aspergillosis

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AU - Kim, Seok Jin

AU - Kang, Eun Hae

AU - Seo, Bo Kyoung

AU - Rho, Kyoung Ho

AU - Chae, Yang Seok

AU - Kim, Byung Soo

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AB - Pseudomembranous necrotizing bronchial aspergillosis (PNBA) is a rare form of invasive aspergillosis with a very poor prognosis. The symptoms are non-specific, and the necrotizing plugs cause airway obstruction. Atelectasis and respiratory failure can be the initial manifestations. Recently, we treated an immunocompromised patient with PNBA, who presented with a sudden onset of atelectasis and acute respiratory failure. There were no preceding signs except for a mild cough and one febrile episode. Bronchoscopy revealed PNBA, and Aspergillus nidulans was cultured from the bronchial wash.

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