SU‐FF‐T‐59: A Simple Scoring Method of Dose Homogeneity for IMRT Treatment Planning

Myonggeun Yoon, D. Shin, S. Park, S. Lee, T. Kim, D. Kim, K. Cho

Research output: Contribution to journalArticle

Abstract

Purpose: The goal of this study was to develop new index for effectively evaluating dose homogeneity with the target‐volume dose—volume histogram (DVH) of intensity‐modulated radiotherapy (IMRT) treatment plans. Method and Materials: The newly defined homogeneity index for assessing dose homogeneity in a target volume, named the sigma‐index (s‐index), was developed using a normalized differential‐DVH (dDVH) with statistical analysis. Results: The s‐index, determined as the standard deviation of the normalized dDVH, was found to vary from 0.80 to 3.15 for the DVHs of brain tumor at out institution. It has been shown that the dose homogeneity for target volume could be also evaluated based on the functional approximation of a target volume DVH to a modified step function and a normalized differential‐DVH to a Gaussian function. The s‐index was compared with these functional approximations in addition to the conventional homogeneity indices. Conclusions: The results showed that the s‐index gives a consistent method for quantifying the degree of homogeneity and has been demonstrated to be more accurate than the conventional methods in evaluating the dose homogeneity. A guide line of the treatment plan based on dose homogeneity is discussed with relation to equivalent uniform dose (EUD).

Original languageEnglish
Pages (from-to)2062
Number of pages1
JournalMedical Physics
Volume33
Issue number6
DOIs
Publication statusPublished - 2006
Externally publishedYes

Fingerprint

Research Design
Radiotherapy
Brain Neoplasms
Therapeutics

ASJC Scopus subject areas

  • Biophysics
  • Radiology Nuclear Medicine and imaging

Cite this

SU‐FF‐T‐59 : A Simple Scoring Method of Dose Homogeneity for IMRT Treatment Planning. / Yoon, Myonggeun; Shin, D.; Park, S.; Lee, S.; Kim, T.; Kim, D.; Cho, K.

In: Medical Physics, Vol. 33, No. 6, 2006, p. 2062.

Research output: Contribution to journalArticle

Yoon, Myonggeun ; Shin, D. ; Park, S. ; Lee, S. ; Kim, T. ; Kim, D. ; Cho, K. / SU‐FF‐T‐59 : A Simple Scoring Method of Dose Homogeneity for IMRT Treatment Planning. In: Medical Physics. 2006 ; Vol. 33, No. 6. pp. 2062.
@article{b972e66ea52c4efb9d5b92e81fdd38d1,
title = "SU‐FF‐T‐59: A Simple Scoring Method of Dose Homogeneity for IMRT Treatment Planning",
abstract = "Purpose: The goal of this study was to develop new index for effectively evaluating dose homogeneity with the target‐volume dose—volume histogram (DVH) of intensity‐modulated radiotherapy (IMRT) treatment plans. Method and Materials: The newly defined homogeneity index for assessing dose homogeneity in a target volume, named the sigma‐index (s‐index), was developed using a normalized differential‐DVH (dDVH) with statistical analysis. Results: The s‐index, determined as the standard deviation of the normalized dDVH, was found to vary from 0.80 to 3.15 for the DVHs of brain tumor at out institution. It has been shown that the dose homogeneity for target volume could be also evaluated based on the functional approximation of a target volume DVH to a modified step function and a normalized differential‐DVH to a Gaussian function. The s‐index was compared with these functional approximations in addition to the conventional homogeneity indices. Conclusions: The results showed that the s‐index gives a consistent method for quantifying the degree of homogeneity and has been demonstrated to be more accurate than the conventional methods in evaluating the dose homogeneity. A guide line of the treatment plan based on dose homogeneity is discussed with relation to equivalent uniform dose (EUD).",
author = "Myonggeun Yoon and D. Shin and S. Park and S. Lee and T. Kim and D. Kim and K. Cho",
year = "2006",
doi = "10.1118/1.2240987",
language = "English",
volume = "33",
pages = "2062",
journal = "Medical Physics",
issn = "0094-2405",
publisher = "AAPM - American Association of Physicists in Medicine",
number = "6",

}

TY - JOUR

T1 - SU‐FF‐T‐59

T2 - A Simple Scoring Method of Dose Homogeneity for IMRT Treatment Planning

AU - Yoon, Myonggeun

AU - Shin, D.

AU - Park, S.

AU - Lee, S.

AU - Kim, T.

AU - Kim, D.

AU - Cho, K.

PY - 2006

Y1 - 2006

N2 - Purpose: The goal of this study was to develop new index for effectively evaluating dose homogeneity with the target‐volume dose—volume histogram (DVH) of intensity‐modulated radiotherapy (IMRT) treatment plans. Method and Materials: The newly defined homogeneity index for assessing dose homogeneity in a target volume, named the sigma‐index (s‐index), was developed using a normalized differential‐DVH (dDVH) with statistical analysis. Results: The s‐index, determined as the standard deviation of the normalized dDVH, was found to vary from 0.80 to 3.15 for the DVHs of brain tumor at out institution. It has been shown that the dose homogeneity for target volume could be also evaluated based on the functional approximation of a target volume DVH to a modified step function and a normalized differential‐DVH to a Gaussian function. The s‐index was compared with these functional approximations in addition to the conventional homogeneity indices. Conclusions: The results showed that the s‐index gives a consistent method for quantifying the degree of homogeneity and has been demonstrated to be more accurate than the conventional methods in evaluating the dose homogeneity. A guide line of the treatment plan based on dose homogeneity is discussed with relation to equivalent uniform dose (EUD).

AB - Purpose: The goal of this study was to develop new index for effectively evaluating dose homogeneity with the target‐volume dose—volume histogram (DVH) of intensity‐modulated radiotherapy (IMRT) treatment plans. Method and Materials: The newly defined homogeneity index for assessing dose homogeneity in a target volume, named the sigma‐index (s‐index), was developed using a normalized differential‐DVH (dDVH) with statistical analysis. Results: The s‐index, determined as the standard deviation of the normalized dDVH, was found to vary from 0.80 to 3.15 for the DVHs of brain tumor at out institution. It has been shown that the dose homogeneity for target volume could be also evaluated based on the functional approximation of a target volume DVH to a modified step function and a normalized differential‐DVH to a Gaussian function. The s‐index was compared with these functional approximations in addition to the conventional homogeneity indices. Conclusions: The results showed that the s‐index gives a consistent method for quantifying the degree of homogeneity and has been demonstrated to be more accurate than the conventional methods in evaluating the dose homogeneity. A guide line of the treatment plan based on dose homogeneity is discussed with relation to equivalent uniform dose (EUD).

UR - http://www.scopus.com/inward/record.url?scp=85024807689&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85024807689&partnerID=8YFLogxK

U2 - 10.1118/1.2240987

DO - 10.1118/1.2240987

M3 - Article

AN - SCOPUS:85024807689

VL - 33

SP - 2062

JO - Medical Physics

JF - Medical Physics

SN - 0094-2405

IS - 6

ER -