@article{565ff18d7b004ad6a70e9bd3fb721546,
title = "Super-Absorbent Polymer Valves and Colorimetric Chemistries for Time-Sequenced Discrete Sampling and Chloride Analysis of Sweat via Skin-Mounted Soft Microfluidics",
abstract = "This paper introduces super absorbent polymer valves and colorimetric sensing reagents as enabling components of soft, skin-mounted microfluidic devices designed to capture, store, and chemically analyze sweat released from eccrine glands. The valving technology enables robust means for guiding the flow of sweat from an inlet location into a collection of isolated reservoirs, in a well-defined sequence. Analysis in these reservoirs involves a color responsive indicator of chloride concentration with a formulation tailored to offer stable operation with sensitivity optimized for the relevant physiological range. Evaluations on human subjects with comparisons against ex situ analysis illustrate the practical utility of these advances.",
keywords = "microfluidics, perspiration, super absorbent polymer, sweat chloride",
author = "Kim, {Sung Bong} and Yi Zhang and Won, {Sang Min} and Bandodkar, {Amay J.} and Yurina Sekine and Yeguang Xue and Jahyun Koo and Harshman, {Sean W.} and Martin, {Jennifer A.} and Park, {Jeong Min} and Ray, {Tyler R.} and Crawford, {Kaitlyn E.} and Lee, {Kyu Tae} and Jungil Choi and Pitsch, {Rhonda L.} and Grigsby, {Claude C.} and Strang, {Adam J.} and Chen, {Yu Yu} and Shuai Xu and Jeonghyun Kim and Ahyeon Koh and Ha, {Jeong Sook} and Yonggang Huang and Kim, {Seung Wook} and Rogers, {John A.}",
note = "Funding Information: S.B.K. and Y.Z. contributed equally to this work. This research was funded by the Air Force Research Laboratory (AFRL) Human Signatures Branch through Core funds provided to Northwestern University under contract FA8650-14-D-6516 and Industrial Strategic Technology Development Program (10051513) funded by the Ministry of Trade, Industry and Energy (MI, Korea). The authors appreciate the members of Bioprocess Engineering Lab in Korea University helped this research. Also, Y.H. acknowledges the support from NSF (Grant Nos. 1400169, 1534120 and 1635443) and NIH (Grant No. R01EB019337). Y.X. gratefully acknowledges support from the Ryan Fellowship and the Northwestern University International Institute for Nanotechnology.",
year = "2018",
month = mar,
day = "22",
doi = "10.1002/smll.201703334",
language = "English",
volume = "14",
journal = "Small",
issn = "1613-6810",
publisher = "Wiley-VCH Verlag",
number = "12",
}