Abstract
Antibody-conjugated hollow gold nanospheres (HGNs) have been used for the SERS imaging of HER2 cancer markers overexpressed in single MCF7 cells. SERS mapping images show that HGNs have much better homogeneous scattering properties than silver nanoparticles. The results demonstrate the potential feasibility of HGNs as highly sensitive and homogeneous sensing probes for biological imaging of cancer markers in live cells.
Original language | English |
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Pages (from-to) | 2260-2263 |
Number of pages | 4 |
Journal | Biosensors and Bioelectronics |
Volume | 24 |
Issue number | 7 |
DOIs | |
Publication status | Published - 2009 Mar 15 |
Keywords
- Cancer marker
- Cellular imaging
- Hollow gold nanosphere
- Homogeneous sensing probe
- Surface-enhanced Raman scattering
ASJC Scopus subject areas
- Biotechnology
- Biophysics
- Biomedical Engineering
- Electrochemistry