Surface-enhanced Raman scattering imaging of HER2 cancer markers overexpressed in single MCF7 cells using antibody conjugated hollow gold nanospheres

Sangyeop Lee; Hyangah Chon; Moonkwon Lee; Jaebum Choo; Soon Young Shin; Young Han Lee; Im Joo Rhyu; Sang Wook Son; Chil Hwan Oh

doi:10.1016/j.bios.2008.10.018

Surface-enhanced Raman scattering imaging of HER2 cancer markers overexpressed in single MCF7 cells using antibody conjugated hollow gold nanospheres

Sangyeop Lee, Hyangah Chon, Moonkwon Lee, Jaebum Choo, Soon Young Shin, Young Han Lee, Im Joo Rhyu, Sang Wook Son, Chil Hwan Oh

Department of Biomedical Sciences

Research output: Contribution to journal › Article › peer-review

149 Citations (Scopus)

Abstract

Antibody-conjugated hollow gold nanospheres (HGNs) have been used for the SERS imaging of HER2 cancer markers overexpressed in single MCF7 cells. SERS mapping images show that HGNs have much better homogeneous scattering properties than silver nanoparticles. The results demonstrate the potential feasibility of HGNs as highly sensitive and homogeneous sensing probes for biological imaging of cancer markers in live cells.

Original language	English
Pages (from-to)	2260-2263
Number of pages	4
Journal	Biosensors and Bioelectronics
Volume	24
Issue number	7
DOIs	https://doi.org/10.1016/j.bios.2008.10.018
Publication status	Published - 2009 Mar 15

Keywords

Cancer marker
Cellular imaging
Hollow gold nanosphere
Homogeneous sensing probe
Surface-enhanced Raman scattering

ASJC Scopus subject areas

Biotechnology
Biophysics
Biomedical Engineering
Electrochemistry

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Surface-enhanced Raman scattering imaging of HER2 cancer markers overexpressed in single MCF7 cells using antibody conjugated hollow gold nanospheres. / Lee, Sangyeop; Chon, Hyangah; Lee, Moonkwon; Choo, Jaebum; Shin, Soon Young; Lee, Young Han; Rhyu, Im Joo ; Son, Sang Wook; Oh, Chil Hwan.

In: Biosensors and Bioelectronics, Vol. 24, No. 7, 15.03.2009, p. 2260-2263.

Research output: Contribution to journal › Article › peer-review

Lee, Sangyeop ; Chon, Hyangah ; Lee, Moonkwon ; Choo, Jaebum ; Shin, Soon Young ; Lee, Young Han ; Rhyu, Im Joo ; Son, Sang Wook ; Oh, Chil Hwan. / Surface-enhanced Raman scattering imaging of HER2 cancer markers overexpressed in single MCF7 cells using antibody conjugated hollow gold nanospheres. In: Biosensors and Bioelectronics. 2009 ; Vol. 24, No. 7. pp. 2260-2263.

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AU - Lee, Young Han

AU - Rhyu, Im Joo

AU - Son, Sang Wook

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