Abstract
Antibody-conjugated hollow gold nanospheres (HGNs) have been used for the SERS imaging of HER2 cancer markers overexpressed in single MCF7 cells. SERS mapping images show that HGNs have much better homogeneous scattering properties than silver nanoparticles. The results demonstrate the potential feasibility of HGNs as highly sensitive and homogeneous sensing probes for biological imaging of cancer markers in live cells.
| Original language | English |
|---|---|
| Pages (from-to) | 2260-2263 |
| Number of pages | 4 |
| Journal | Biosensors and Bioelectronics |
| Volume | 24 |
| Issue number | 7 |
| DOIs | |
| Publication status | Published - 2009 Mar 15 |
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Keywords
- Cancer marker
- Cellular imaging
- Hollow gold nanosphere
- Homogeneous sensing probe
- Surface-enhanced Raman scattering
ASJC Scopus subject areas
- Biophysics
- Biomedical Engineering
- Biotechnology
- Electrochemistry
Cite this
Surface-enhanced Raman scattering imaging of HER2 cancer markers overexpressed in single MCF7 cells using antibody conjugated hollow gold nanospheres. / Lee, Sangyeop; Chon, Hyangah; Lee, Moonkwon; Choo, Jaebum; Shin, Soon Young; Lee, Young Han; Rhyu, Im Joo; Son, Sang Wook; Oh, Chil Hwan.
In: Biosensors and Bioelectronics, Vol. 24, No. 7, 15.03.2009, p. 2260-2263.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Surface-enhanced Raman scattering imaging of HER2 cancer markers overexpressed in single MCF7 cells using antibody conjugated hollow gold nanospheres
AU - Lee, Sangyeop
AU - Chon, Hyangah
AU - Lee, Moonkwon
AU - Choo, Jaebum
AU - Shin, Soon Young
AU - Lee, Young Han
AU - Rhyu, Im Joo
AU - Son, Sang Wook
AU - Oh, Chil Hwan
PY - 2009/3/15
Y1 - 2009/3/15
N2 - Antibody-conjugated hollow gold nanospheres (HGNs) have been used for the SERS imaging of HER2 cancer markers overexpressed in single MCF7 cells. SERS mapping images show that HGNs have much better homogeneous scattering properties than silver nanoparticles. The results demonstrate the potential feasibility of HGNs as highly sensitive and homogeneous sensing probes for biological imaging of cancer markers in live cells.
AB - Antibody-conjugated hollow gold nanospheres (HGNs) have been used for the SERS imaging of HER2 cancer markers overexpressed in single MCF7 cells. SERS mapping images show that HGNs have much better homogeneous scattering properties than silver nanoparticles. The results demonstrate the potential feasibility of HGNs as highly sensitive and homogeneous sensing probes for biological imaging of cancer markers in live cells.
KW - Cancer marker
KW - Cellular imaging
KW - Hollow gold nanosphere
KW - Homogeneous sensing probe
KW - Surface-enhanced Raman scattering
UR - http://www.scopus.com/inward/record.url?scp=60349119849&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=60349119849&partnerID=8YFLogxK
U2 - 10.1016/j.bios.2008.10.018
DO - 10.1016/j.bios.2008.10.018
M3 - Article
VL - 24
SP - 2260
EP - 2263
JO - Biosensors
JF - Biosensors
SN - 0956-5663
IS - 7
ER -