Surgical outcomes and prognostic factors for T4 gastric cancers

Jong Han Kim, You Jin Jang, Sung Soo Park, Seong Heum Park, Seung Joo Kim, Young Jae Mok, Chong Suk Kim

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

PURPOSE: In locally advanced gastric carcinomas that have invaded adjacent organs, the prognosis is poor. When combined resections are performed in T4 gastric cancers, a high morbidity rate is reported and it is inconclusive as to whether or not there is an improvement in the survival rate. We investigated surgical outcomes and analysed the prognostic factors for T4 gastric cancers. PATIENTS AND METHODS: Between January 1992 and December 2000, 132 patients underwent surgery for T4 gastric cancer; they were divided into three groups: combined resections in group I, gastrectomy alone in group II, and resections not performed but palliative gastrojejunostomy or intraperitoneal chemotherapy in group III. Surgical outcomes and clinicopathologic factors were compared and prognostic factors were evaluated. RESULTS: Among the three groups, statistically significantly different factors were tumour location, Borrmann type, tumour size, distant metastasis and peritoneal metastasis. The most commonly resected organ was the transverse colon, and 14 post-operative morbidities developed. In the multivariate analysis, the treatment group and curability were proved to be independent prognostic factors. CONCLUSION: In patients with T4 gastric carcinoma, an aggressive surgical approach can be beneficial when curative resection is performed. If curative resection is not possible, palliative resection can be performed for a better quality of life.

Original languageEnglish
Pages (from-to)198-204
Number of pages7
JournalAsian Journal of Surgery
Volume32
Issue number4
DOIs
Publication statusPublished - 2009 Oct

Keywords

  • Prognostic factors
  • Surgical resection
  • T4 gastric cancer

ASJC Scopus subject areas

  • Surgery

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  • Cite this

    Kim, J. H., Jang, Y. J., Park, S. S., Park, S. H., Kim, S. J., Mok, Y. J., & Kim, C. S. (2009). Surgical outcomes and prognostic factors for T4 gastric cancers. Asian Journal of Surgery, 32(4), 198-204. https://doi.org/10.1016/S1015-9584(09)60395-X