Sympathetic sprouting in sensory ganglia depends on the number of injured neurons

Jin Kim Hee Jin Kim, Heung Sik Na, Keun Back Seung Keun Back, Kil Hong Seung Kil Hong

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

We examined whether the extent of sympathetic sprouting in the dorsal root ganglion was a function of the number of injured nerve fibers. We compared two groups of rats. One group was subjected to unilateral superior and inferior caudal trunk transections at the level between the S1 and S2 spinal nerves (S-I group) and the other group was subjected to unilateral superior caudal trunk transection at the same level (S group). Immunohistochemical staining with tyrosine hydroxylase (TH) antibody of the S1 DRG revealed that the degree of TH-immunoreactive fibers was more extensive in the S-I group than in the S group. However, there was no difference in the severity of neuropathic pain behaviors between the two groups. These results suggest that the extent of sympathetic sprouting in the DRG following peripheral nerve injury is proportionally related to the amount of injured nerve fibers, but not related to the degree of neuropathic pain behaviors.

Original languageEnglish
Pages (from-to)3529-3532
Number of pages4
JournalNeuroReport
Volume12
Issue number16
Publication statusPublished - 2001 Nov 16

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Sensory Ganglia
Diagnosis-Related Groups
Tyrosine 3-Monooxygenase
Neuralgia
Nerve Fibers
Neurons
Peripheral Nerve Injuries
Spinal Nerves
Spinal Ganglia
Staining and Labeling
Antibodies

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Hee Jin Kim, J. K., Na, H. S., Seung Keun Back, K. B., & Seung Kil Hong, K. H. (2001). Sympathetic sprouting in sensory ganglia depends on the number of injured neurons. NeuroReport, 12(16), 3529-3532.

Sympathetic sprouting in sensory ganglia depends on the number of injured neurons. / Hee Jin Kim, Jin Kim; Na, Heung Sik; Seung Keun Back, Keun Back; Seung Kil Hong, Kil Hong.

In: NeuroReport, Vol. 12, No. 16, 16.11.2001, p. 3529-3532.

Research output: Contribution to journalArticle

Hee Jin Kim, JK, Na, HS, Seung Keun Back, KB & Seung Kil Hong, KH 2001, 'Sympathetic sprouting in sensory ganglia depends on the number of injured neurons', NeuroReport, vol. 12, no. 16, pp. 3529-3532.
Hee Jin Kim JK, Na HS, Seung Keun Back KB, Seung Kil Hong KH. Sympathetic sprouting in sensory ganglia depends on the number of injured neurons. NeuroReport. 2001 Nov 16;12(16):3529-3532.
Hee Jin Kim, Jin Kim ; Na, Heung Sik ; Seung Keun Back, Keun Back ; Seung Kil Hong, Kil Hong. / Sympathetic sprouting in sensory ganglia depends on the number of injured neurons. In: NeuroReport. 2001 ; Vol. 12, No. 16. pp. 3529-3532.
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