Synchronized reverberatory bursting activity in cultured network of rat cortical neurons

Joon Ho Choi, June Hoan Kim, Kyoung Jin Lee, Byoung Kab Lee, James Jungho Pak

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

We have investigated spatially distributed dynamics that arises in cultured networks of cortical neurons of rats over two weeks by using a home-built multi-electrode array (MEA) plate recording system. The spiking dynamics detected through the MEA electrodes is typically a mixed signal of random single firing events and reverberating bursting events. The bursting activities seem to arise only when some degree of networking is established. Our analysis also indicates that the bursting activity spreads out in space gradually over days and becomes globally synchronized by the time the culture reaches approximately 10 days in vitro.

Original languageEnglish
Pages (from-to)S212-S216
JournalJournal of the Korean Physical Society
Volume48
Issue numberSUPPL. 2
Publication statusPublished - 2006 Feb

Keywords

  • Biological neural network
  • Dynamical system
  • Synchronization

ASJC Scopus subject areas

  • Physics and Astronomy(all)

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