Synchronous double primary cancers associated with a choledochal cyst and anomalous pancreaticobiliary ductal union

Kang Kook Choi, Sae Byeol Choi, Seung Woo Park, Hyun Ki Kim, Young Nyun Park, Kyung Sik Kim

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A 60-year-old female was admitted with epigastric pain lasting a month. Preoperative diagnosis was choledochal cyst with anomalous pancreaticobiliaryductal union (APBDU), C-P type. A papillary mass measuring 2.5 × 1.9 cm was found adjacent to the pancreaticocholedochal junction. Gallbladder (GB) cancer was also observed. Pyloric-preserving pancreaticoduodenectomy (PPPD) was performed. The patient received adjuvant chemotherapy/radiation therapy on the tumor bed. The gallbladder cancer showed serosal invasion, while the bile duct cancer extended into the pancreas. Although common bile duct (CBD) cancer lesion showed focally positive for p53 and the gallbladder cancer lesion showed negative for p53, the Ki-67 labeling index of the CBD cancer and GB cancer were about 10% and 30%, respectively. Nine months after curative resection, a stricture on the subhepatic colon developed due to adjuvant radiation therapy. Localized peritoneal seedings were incidentally found during a right hemicolectomy. The patient underwent chemotherapy and had no evidence of tumor recurrence for two years after PPPD.

Original languageEnglish
Pages (from-to)281-286
Number of pages6
JournalJournal of the Korean Surgical Society
Issue number4
Publication statusPublished - 2011 Oct 1



  • Bile duct neoplasms
  • Choledochal cyst
  • Gallbladder neoplsms
  • Synchronous multiple primary neoplasms

ASJC Scopus subject areas

  • Surgery

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