Synchronous double primary cancers associated with a choledochal cyst and anomalous pancreaticobiliary ductal union

Kang Kook Choi, Sae-Byeol Choi, Seung Woo Park, Hyun Ki Kim, Young Nyun Park, Kyung Sik Kim

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

A 60-year-old female was admitted with epigastric pain lasting a month. Preoperative diagnosis was choledochal cyst with anomalous pancreaticobiliaryductal union (APBDU), C-P type. A papillary mass measuring 2.5 × 1.9 cm was found adjacent to the pancreaticocholedochal junction. Gallbladder (GB) cancer was also observed. Pyloric-preserving pancreaticoduodenectomy (PPPD) was performed. The patient received adjuvant chemotherapy/radiation therapy on the tumor bed. The gallbladder cancer showed serosal invasion, while the bile duct cancer extended into the pancreas. Although common bile duct (CBD) cancer lesion showed focally positive for p53 and the gallbladder cancer lesion showed negative for p53, the Ki-67 labeling index of the CBD cancer and GB cancer were about 10% and 30%, respectively. Nine months after curative resection, a stricture on the subhepatic colon developed due to adjuvant radiation therapy. Localized peritoneal seedings were incidentally found during a right hemicolectomy. The patient underwent chemotherapy and had no evidence of tumor recurrence for two years after PPPD.

Original languageEnglish
Pages (from-to)281-286
Number of pages6
JournalJournal of the Korean Surgical Society
Volume81
Issue number4
DOIs
Publication statusPublished - 2011 Oct 1

Fingerprint

Choledochal Cyst
Gallbladder Neoplasms
Bile Duct Neoplasms
Pancreaticoduodenectomy
Common Bile Duct
Neoplasms
Radiotherapy
Adjuvant Chemotherapy
Pancreas
Pathologic Constriction
Colon
Recurrence
Drug Therapy
Pain

Keywords

  • Bile duct neoplasms
  • Choledochal cyst
  • Gallbladder neoplsms
  • Synchronous multiple primary neoplasms

ASJC Scopus subject areas

  • Surgery

Cite this

Synchronous double primary cancers associated with a choledochal cyst and anomalous pancreaticobiliary ductal union. / Choi, Kang Kook; Choi, Sae-Byeol; Park, Seung Woo; Kim, Hyun Ki; Park, Young Nyun; Kim, Kyung Sik.

In: Journal of the Korean Surgical Society, Vol. 81, No. 4, 01.10.2011, p. 281-286.

Research output: Contribution to journalArticle

Choi, Kang Kook ; Choi, Sae-Byeol ; Park, Seung Woo ; Kim, Hyun Ki ; Park, Young Nyun ; Kim, Kyung Sik. / Synchronous double primary cancers associated with a choledochal cyst and anomalous pancreaticobiliary ductal union. In: Journal of the Korean Surgical Society. 2011 ; Vol. 81, No. 4. pp. 281-286.
@article{6cc35e23df57413c8d79f26ff87a262c,
title = "Synchronous double primary cancers associated with a choledochal cyst and anomalous pancreaticobiliary ductal union",
abstract = "A 60-year-old female was admitted with epigastric pain lasting a month. Preoperative diagnosis was choledochal cyst with anomalous pancreaticobiliaryductal union (APBDU), C-P type. A papillary mass measuring 2.5 × 1.9 cm was found adjacent to the pancreaticocholedochal junction. Gallbladder (GB) cancer was also observed. Pyloric-preserving pancreaticoduodenectomy (PPPD) was performed. The patient received adjuvant chemotherapy/radiation therapy on the tumor bed. The gallbladder cancer showed serosal invasion, while the bile duct cancer extended into the pancreas. Although common bile duct (CBD) cancer lesion showed focally positive for p53 and the gallbladder cancer lesion showed negative for p53, the Ki-67 labeling index of the CBD cancer and GB cancer were about 10{\%} and 30{\%}, respectively. Nine months after curative resection, a stricture on the subhepatic colon developed due to adjuvant radiation therapy. Localized peritoneal seedings were incidentally found during a right hemicolectomy. The patient underwent chemotherapy and had no evidence of tumor recurrence for two years after PPPD.",
keywords = "Bile duct neoplasms, Choledochal cyst, Gallbladder neoplsms, Synchronous multiple primary neoplasms",
author = "Choi, {Kang Kook} and Sae-Byeol Choi and Park, {Seung Woo} and Kim, {Hyun Ki} and Park, {Young Nyun} and Kim, {Kyung Sik}",
year = "2011",
month = "10",
day = "1",
doi = "10.4174/jkss.2011.81.4.281",
language = "English",
volume = "81",
pages = "281--286",
journal = "Annals of Surgical Treatment and Research",
issn = "2288-6575",
publisher = "Korean Surgical Society",
number = "4",

}

TY - JOUR

T1 - Synchronous double primary cancers associated with a choledochal cyst and anomalous pancreaticobiliary ductal union

AU - Choi, Kang Kook

AU - Choi, Sae-Byeol

AU - Park, Seung Woo

AU - Kim, Hyun Ki

AU - Park, Young Nyun

AU - Kim, Kyung Sik

PY - 2011/10/1

Y1 - 2011/10/1

N2 - A 60-year-old female was admitted with epigastric pain lasting a month. Preoperative diagnosis was choledochal cyst with anomalous pancreaticobiliaryductal union (APBDU), C-P type. A papillary mass measuring 2.5 × 1.9 cm was found adjacent to the pancreaticocholedochal junction. Gallbladder (GB) cancer was also observed. Pyloric-preserving pancreaticoduodenectomy (PPPD) was performed. The patient received adjuvant chemotherapy/radiation therapy on the tumor bed. The gallbladder cancer showed serosal invasion, while the bile duct cancer extended into the pancreas. Although common bile duct (CBD) cancer lesion showed focally positive for p53 and the gallbladder cancer lesion showed negative for p53, the Ki-67 labeling index of the CBD cancer and GB cancer were about 10% and 30%, respectively. Nine months after curative resection, a stricture on the subhepatic colon developed due to adjuvant radiation therapy. Localized peritoneal seedings were incidentally found during a right hemicolectomy. The patient underwent chemotherapy and had no evidence of tumor recurrence for two years after PPPD.

AB - A 60-year-old female was admitted with epigastric pain lasting a month. Preoperative diagnosis was choledochal cyst with anomalous pancreaticobiliaryductal union (APBDU), C-P type. A papillary mass measuring 2.5 × 1.9 cm was found adjacent to the pancreaticocholedochal junction. Gallbladder (GB) cancer was also observed. Pyloric-preserving pancreaticoduodenectomy (PPPD) was performed. The patient received adjuvant chemotherapy/radiation therapy on the tumor bed. The gallbladder cancer showed serosal invasion, while the bile duct cancer extended into the pancreas. Although common bile duct (CBD) cancer lesion showed focally positive for p53 and the gallbladder cancer lesion showed negative for p53, the Ki-67 labeling index of the CBD cancer and GB cancer were about 10% and 30%, respectively. Nine months after curative resection, a stricture on the subhepatic colon developed due to adjuvant radiation therapy. Localized peritoneal seedings were incidentally found during a right hemicolectomy. The patient underwent chemotherapy and had no evidence of tumor recurrence for two years after PPPD.

KW - Bile duct neoplasms

KW - Choledochal cyst

KW - Gallbladder neoplsms

KW - Synchronous multiple primary neoplasms

UR - http://www.scopus.com/inward/record.url?scp=81055136617&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=81055136617&partnerID=8YFLogxK

U2 - 10.4174/jkss.2011.81.4.281

DO - 10.4174/jkss.2011.81.4.281

M3 - Article

VL - 81

SP - 281

EP - 286

JO - Annals of Surgical Treatment and Research

JF - Annals of Surgical Treatment and Research

SN - 2288-6575

IS - 4

ER -