Abstract
Reducing the enzyme loadings for enzymatic saccharification of lignocellulose is required for economically feasible production of biofuels and biochemicals. One strategy is addition of small amounts of synergistic proteins to cellulase mixtures. Synergistic proteins increase the activity of cellulase without causing significant hydrolysis of cellulose. Synergistic proteins exert their activity by inducing structural modifications in cellulose. Recently, synergistic proteins from various biological sources, including bacteria, fungi, and plants, were identified based on genomic data, and their synergistic activities were investigated. Currently, an up-to-date overview of several aspects of synergistic proteins, such as their functions, action mechanisms and synergistic activity, are important for future industrial application. In this review, we summarize the current state of research on four synergistic proteins: carbohydrate-binding modules, plant expansins, expansin-like proteins, and Auxiliary Activity family 9 (formerly GH61) proteins. This review provides critical information to aid in promoting research on the development of efficient and industrially feasible synergistic proteins.
| Original language | English |
|---|---|
| Pages (from-to) | 8469-8480 |
| Number of pages | 12 |
| Journal | Applied Microbiology and Biotechnology |
| Volume | 98 |
| Issue number | 20 |
| DOIs | |
| Publication status | Published - 2014 Jan 1 |
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ASJC Scopus subject areas
- Biotechnology
- Applied Microbiology and Biotechnology
Cite this
Synergistic proteins for the enhanced enzymatic hydrolysis of cellulose by cellulase. / Kim, In Jung; Lee, Hee Jin; Choi, In-Geol; Kim, Kyoung Heon.
In: Applied Microbiology and Biotechnology, Vol. 98, No. 20, 01.01.2014, p. 8469-8480.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Synergistic proteins for the enhanced enzymatic hydrolysis of cellulose by cellulase
AU - Kim, In Jung
AU - Lee, Hee Jin
AU - Choi, In-Geol
AU - Kim, Kyoung Heon
PY - 2014/1/1
Y1 - 2014/1/1
N2 - Reducing the enzyme loadings for enzymatic saccharification of lignocellulose is required for economically feasible production of biofuels and biochemicals. One strategy is addition of small amounts of synergistic proteins to cellulase mixtures. Synergistic proteins increase the activity of cellulase without causing significant hydrolysis of cellulose. Synergistic proteins exert their activity by inducing structural modifications in cellulose. Recently, synergistic proteins from various biological sources, including bacteria, fungi, and plants, were identified based on genomic data, and their synergistic activities were investigated. Currently, an up-to-date overview of several aspects of synergistic proteins, such as their functions, action mechanisms and synergistic activity, are important for future industrial application. In this review, we summarize the current state of research on four synergistic proteins: carbohydrate-binding modules, plant expansins, expansin-like proteins, and Auxiliary Activity family 9 (formerly GH61) proteins. This review provides critical information to aid in promoting research on the development of efficient and industrially feasible synergistic proteins.
AB - Reducing the enzyme loadings for enzymatic saccharification of lignocellulose is required for economically feasible production of biofuels and biochemicals. One strategy is addition of small amounts of synergistic proteins to cellulase mixtures. Synergistic proteins increase the activity of cellulase without causing significant hydrolysis of cellulose. Synergistic proteins exert their activity by inducing structural modifications in cellulose. Recently, synergistic proteins from various biological sources, including bacteria, fungi, and plants, were identified based on genomic data, and their synergistic activities were investigated. Currently, an up-to-date overview of several aspects of synergistic proteins, such as their functions, action mechanisms and synergistic activity, are important for future industrial application. In this review, we summarize the current state of research on four synergistic proteins: carbohydrate-binding modules, plant expansins, expansin-like proteins, and Auxiliary Activity family 9 (formerly GH61) proteins. This review provides critical information to aid in promoting research on the development of efficient and industrially feasible synergistic proteins.
KW - Auxiliary Activity family 9
KW - Carbohydrate-binding module
KW - Cellulase
KW - Cellulose hydrolysis
KW - Expansin
KW - GH61
KW - Synergistic protein
UR - http://www.scopus.com/inward/record.url?scp=84920254305&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84920254305&partnerID=8YFLogxK
U2 - 10.1007/s00253-014-6001-3
DO - 10.1007/s00253-014-6001-3
M3 - Article
C2 - 25129610
AN - SCOPUS:84920254305
VL - 98
SP - 8469
EP - 8480
JO - Applied Microbiology and Biotechnology
JF - Applied Microbiology and Biotechnology
SN - 0175-7598
IS - 20
ER -