Synthesis and characteristics of polyelectrolyte complexes composed of chitosan and hyaluronic acid

Seon Jeong Kim, Su Ryon Shin, Kyu Back Lee, Yong Doo Park, Sun I. Kim

Research output: Contribution to journalArticle

30 Citations (Scopus)

Abstract

Polyelectrolyte complexes (PEC) composed of various weight ratios of chitosan and hyaluronic acid (HA) were prepared. The PECs were formed by a reaction of the oppositely charged polymers. The characterizations of the PEC films were investigated by using Fourier transform infrared spectroscopy (FTIR) and differential scanning calorimetry (DSC). The PECs were found to swell rapidly, reaching equilibrium within 30 min, and exhibited relatively high swelling ratios of 250-325% at room temperature. The swelling ratio increased when the pH of the buffer was below pH 6, as a result of the dissociation of the ionic bonds, and with increments of temperature. Therefore, the swelling ratios of the films were pH and temperature dependent. DSC was used to determine the amount of free water in the PEC films, which increased with increasing chitosan content.

Original languageEnglish
Pages (from-to)2908-2913
Number of pages6
JournalJournal of Applied Polymer Science
Volume91
Issue number5
DOIs
Publication statusPublished - 2004 Mar 5

Keywords

  • Chitosan
  • Hyaluronic acid
  • Polyelectrolyte
  • Swelling

ASJC Scopus subject areas

  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Polymers and Plastics
  • Materials Chemistry

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