Synthesis and characteristics of polyelectrolyte complexes composed of chitosan and hyaluronic acid

Seon Jeong Kim, Su Ryon Shin, Kyu Back Lee, Yongdoo Park, Sun I. Kim

Research output: Contribution to journalArticle

30 Citations (Scopus)

Abstract

Polyelectrolyte complexes (PEC) composed of various weight ratios of chitosan and hyaluronic acid (HA) were prepared. The PECs were formed by a reaction of the oppositely charged polymers. The characterizations of the PEC films were investigated by using Fourier transform infrared spectroscopy (FTIR) and differential scanning calorimetry (DSC). The PECs were found to swell rapidly, reaching equilibrium within 30 min, and exhibited relatively high swelling ratios of 250-325% at room temperature. The swelling ratio increased when the pH of the buffer was below pH 6, as a result of the dissociation of the ionic bonds, and with increments of temperature. Therefore, the swelling ratios of the films were pH and temperature dependent. DSC was used to determine the amount of free water in the PEC films, which increased with increasing chitosan content.

Original languageEnglish
Pages (from-to)2908-2913
Number of pages6
JournalJournal of Applied Polymer Science
Volume91
Issue number5
DOIs
Publication statusPublished - 2004 Mar 5

Fingerprint

Hyaluronic acid
Chitosan
Hyaluronic Acid
Polyelectrolytes
Swelling
Differential scanning calorimetry
Temperature
Fourier transform infrared spectroscopy
Buffers
Polymers
Water

Keywords

  • Chitosan
  • Hyaluronic acid
  • Polyelectrolyte
  • Swelling

ASJC Scopus subject areas

  • Polymers and Plastics

Cite this

Synthesis and characteristics of polyelectrolyte complexes composed of chitosan and hyaluronic acid. / Kim, Seon Jeong; Shin, Su Ryon; Lee, Kyu Back; Park, Yongdoo; Kim, Sun I.

In: Journal of Applied Polymer Science, Vol. 91, No. 5, 05.03.2004, p. 2908-2913.

Research output: Contribution to journalArticle

@article{7ed21254f156492a98ecccb78dfbe18d,
title = "Synthesis and characteristics of polyelectrolyte complexes composed of chitosan and hyaluronic acid",
abstract = "Polyelectrolyte complexes (PEC) composed of various weight ratios of chitosan and hyaluronic acid (HA) were prepared. The PECs were formed by a reaction of the oppositely charged polymers. The characterizations of the PEC films were investigated by using Fourier transform infrared spectroscopy (FTIR) and differential scanning calorimetry (DSC). The PECs were found to swell rapidly, reaching equilibrium within 30 min, and exhibited relatively high swelling ratios of 250-325{\%} at room temperature. The swelling ratio increased when the pH of the buffer was below pH 6, as a result of the dissociation of the ionic bonds, and with increments of temperature. Therefore, the swelling ratios of the films were pH and temperature dependent. DSC was used to determine the amount of free water in the PEC films, which increased with increasing chitosan content.",
keywords = "Chitosan, Hyaluronic acid, Polyelectrolyte, Swelling",
author = "Kim, {Seon Jeong} and Shin, {Su Ryon} and Lee, {Kyu Back} and Yongdoo Park and Kim, {Sun I.}",
year = "2004",
month = "3",
day = "5",
doi = "10.1002/app.13513",
language = "English",
volume = "91",
pages = "2908--2913",
journal = "Journal of Applied Polymer Science",
issn = "0021-8995",
publisher = "John Wiley and Sons Inc.",
number = "5",

}

TY - JOUR

T1 - Synthesis and characteristics of polyelectrolyte complexes composed of chitosan and hyaluronic acid

AU - Kim, Seon Jeong

AU - Shin, Su Ryon

AU - Lee, Kyu Back

AU - Park, Yongdoo

AU - Kim, Sun I.

PY - 2004/3/5

Y1 - 2004/3/5

N2 - Polyelectrolyte complexes (PEC) composed of various weight ratios of chitosan and hyaluronic acid (HA) were prepared. The PECs were formed by a reaction of the oppositely charged polymers. The characterizations of the PEC films were investigated by using Fourier transform infrared spectroscopy (FTIR) and differential scanning calorimetry (DSC). The PECs were found to swell rapidly, reaching equilibrium within 30 min, and exhibited relatively high swelling ratios of 250-325% at room temperature. The swelling ratio increased when the pH of the buffer was below pH 6, as a result of the dissociation of the ionic bonds, and with increments of temperature. Therefore, the swelling ratios of the films were pH and temperature dependent. DSC was used to determine the amount of free water in the PEC films, which increased with increasing chitosan content.

AB - Polyelectrolyte complexes (PEC) composed of various weight ratios of chitosan and hyaluronic acid (HA) were prepared. The PECs were formed by a reaction of the oppositely charged polymers. The characterizations of the PEC films were investigated by using Fourier transform infrared spectroscopy (FTIR) and differential scanning calorimetry (DSC). The PECs were found to swell rapidly, reaching equilibrium within 30 min, and exhibited relatively high swelling ratios of 250-325% at room temperature. The swelling ratio increased when the pH of the buffer was below pH 6, as a result of the dissociation of the ionic bonds, and with increments of temperature. Therefore, the swelling ratios of the films were pH and temperature dependent. DSC was used to determine the amount of free water in the PEC films, which increased with increasing chitosan content.

KW - Chitosan

KW - Hyaluronic acid

KW - Polyelectrolyte

KW - Swelling

UR - http://www.scopus.com/inward/record.url?scp=1142305294&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=1142305294&partnerID=8YFLogxK

U2 - 10.1002/app.13513

DO - 10.1002/app.13513

M3 - Article

AN - SCOPUS:1142305294

VL - 91

SP - 2908

EP - 2913

JO - Journal of Applied Polymer Science

JF - Journal of Applied Polymer Science

SN - 0021-8995

IS - 5

ER -