Abstract
A protocol to access 2-aryl-substituted quinolines from readily available 2-iodoanilines and β-chloropropiophenones, which are synthetic equivalents of acrylophenones, has been developed via the palladium-catalyzed cascade reaction. Various 2-iodoanilines and β-chloropropiophenones were applicable to this protocol to afford the desired quinoline products in good to high yields. Moreover, we demonstrated the usefulness of this protocol in direct synthesis of chloride-bridged dimeric iridium complexes, one of the key intermediates in the synthesis of iridium-based phosphorous materials, without the complete isolation of the quinolines.
Original language | English |
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Pages (from-to) | 1631-1636 |
Number of pages | 6 |
Journal | Asian Journal of Organic Chemistry |
Volume | 8 |
Issue number | 9 |
DOIs | |
Publication status | Published - 2019 Sep 1 |
Keywords
- 2-Arylquinolines
- Cascade reaction
- Ligand free
- Palladium
- β-Chloropropiophenone
ASJC Scopus subject areas
- Organic Chemistry