Synthesis of lariat ether carboxylic acids based on dibenzo- 16-crown-5

R. A. Bartsch, C. L. Cowey, S. Elshani, M. J. Goo, V. J. Huber, S. N. Ivy, R. J. Johnson, Jong Seung Kim, E. Luboch, J. A. McDonough, M. J. Pugia, B. Son, Q. Zhao

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Abstract

Synthetic routes to forty-seven dibenzo-16-crown-5 compounds with pendant carboxylic acid groups are reported. When taken together with previously described lariat ether carboxylic acids, these new compounds provide several series with systematic structural variations including changes in the identity and attachment site(s) of one or more lipophilic groups and the length of the spacer that connects the carboxylic acid group to the polyether framework.

Original languageEnglish
Pages (from-to)311-331
Number of pages21
JournalJournal of Heterocyclic Chemistry
Volume38
Issue number2
Publication statusPublished - 2001 Jan 1
Externally publishedYes

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ASJC Scopus subject areas

  • Organic Chemistry

Cite this

Bartsch, R. A., Cowey, C. L., Elshani, S., Goo, M. J., Huber, V. J., Ivy, S. N., Johnson, R. J., Kim, J. S., Luboch, E., McDonough, J. A., Pugia, M. J., Son, B., & Zhao, Q. (2001). Synthesis of lariat ether carboxylic acids based on dibenzo- 16-crown-5. Journal of Heterocyclic Chemistry, 38(2), 311-331.