Synthesis of length-controlled polyvalent silver nanowire-DNA conjugates for sensitive and selective detection of DNA targets

Sang Hun Han, Jae-Seung Lee

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

We have developed a facile method to rapidly synthesize the monodisperse silver nanowire-DNA conjugates with a constant diameter and systematically controllable lengths in the range of 0.5-2.5 μm. The synthesis of silver nanowires takes advantage of poly(sodium 4-styrenesulfonate) as a structure-directing reagent and is performed under very mild conditions such as room temperature and aqueous media. The nanowires are densely conjugated with DNA sequences enough to exhibit the cooperative properties for the sensitive and selective detection of DNA targets. The limit of detection is 50 pM.

Original languageEnglish
Pages (from-to)828-832
Number of pages5
JournalLangmuir
Volume28
Issue number1
DOIs
Publication statusPublished - 2012 Jan 10

Fingerprint

Nanowires
Silver
DNA
nanowires
deoxyribonucleic acid
silver
synthesis
DNA sequences
reagents
Limit of Detection
Sodium
sodium
Temperature
room temperature

ASJC Scopus subject areas

  • Electrochemistry
  • Condensed Matter Physics
  • Surfaces and Interfaces
  • Materials Science(all)
  • Spectroscopy

Cite this

Synthesis of length-controlled polyvalent silver nanowire-DNA conjugates for sensitive and selective detection of DNA targets. / Han, Sang Hun; Lee, Jae-Seung.

In: Langmuir, Vol. 28, No. 1, 10.01.2012, p. 828-832.

Research output: Contribution to journalArticle

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