Synthesis of nano-sized biphasic calcium phosphate ceramics with spherical shape by flame spray pyrolysis

Jung Sang Cho, You Na Ko, Hye Young Koo, Yun Chan Kang

Research output: Contribution to journalArticle

34 Citations (Scopus)

Abstract

Nanometer size biphasic calcium phosphate (BCP) powders with various Ca/P molar ratios satisfied with appropriate phase ratios of HA/β-TCP were prepared by high temperature flame spray pyrolysis process. The BCP powders had spherical shapes and narrow size distributions irrespective of the ratios of Ca/P. The mean size of the BCP powders measured from the TEM image was 38 nm. The composition ratio of Ca/P was controlled from 1.500 to 1.723 in the spray solution, and required phase ratios of HA/TCP are controlled systematically. The calcium dissolution of the pellets obtained from the BCP powders directly prepared by flame spray pyrolysis in buffer solution increased with the decrease of Ca/P ratios except with the Ca/P ratio of 1.713. The pellet surface with Ca/P ratio of 1.500, which consisted of β-TCP, was eroded dramatically for 7 days. On the other hand, the pellet surface with Ca/P ratio of 1.667 was stable and did not disintegrate after immersion in Tris-HCl buffer solution based on the SEM observation.

Original languageEnglish
Pages (from-to)1143-1149
Number of pages7
JournalJournal of Materials Science: Materials in Medicine
Volume21
Issue number4
DOIs
Publication statusPublished - 2010 Apr 1
Externally publishedYes

Fingerprint

calcium phosphates
Spray pyrolysis
Calcium phosphate
Ceramics
Powders
pyrolysis
sprayers
flames
pellets
ceramics
synthesis
Buffers
buffers
Tromethamine
Immersion
submerging
calcium
Calcium
dissolving
Dissolution

ASJC Scopus subject areas

  • Biophysics
  • Bioengineering
  • Biomaterials
  • Biomedical Engineering

Cite this

Synthesis of nano-sized biphasic calcium phosphate ceramics with spherical shape by flame spray pyrolysis. / Cho, Jung Sang; Ko, You Na; Koo, Hye Young; Kang, Yun Chan.

In: Journal of Materials Science: Materials in Medicine, Vol. 21, No. 4, 01.04.2010, p. 1143-1149.

Research output: Contribution to journalArticle

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