Synthesis of rhodamine-labelled dieckol: its unique intracellular localization and potent anti-inflammatory activity

Jong Hwan Kwak, Yanxia He, Byungkwon Yoon, Seyoung Koo, Zhigang Yang, Eun Ju Kang, Bong Ho Lee, Seung Yun Han, Yung Choon Yoo, Kyung Bok Lee, Jong Seung Kim

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10 Citations (Scopus)

Abstract

Rhodamine-labelled dieckol (1) synthesized through a click reaction was found to be localized in the endoplasmic reticulum (ER) of RAW 264.7 cells. Anti-inflammatory activity of compound 1 was considerably greater than that of dieckol itself.

Original languageEnglish
Pages (from-to)13045-13048
Number of pages4
JournalChemical Communications
Volume50
Issue number86
DOIs
Publication statusPublished - 2014 Oct 2

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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  • Cite this

    Kwak, J. H., He, Y., Yoon, B., Koo, S., Yang, Z., Kang, E. J., Lee, B. H., Han, S. Y., Yoo, Y. C., Lee, K. B., & Kim, J. S. (2014). Synthesis of rhodamine-labelled dieckol: its unique intracellular localization and potent anti-inflammatory activity. Chemical Communications, 50(86), 13045-13048. https://doi.org/10.1039/c4cc04270k