Abstract
A pair of artificial DNA bases have now been shown to adopt an edge-to-edge geometry in DNA which is similar that found in WatsonCrick base pairing. Aptamers containing these bases have also been shown to bind more strongly to a target than those developed using only the four naturally occurring bases.
Original language | English |
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Pages (from-to) | 617-619 |
Number of pages | 3 |
Journal | Nature Chemistry |
Volume | 7 |
Issue number | 8 |
DOIs | |
Publication status | Published - 2015 Jul 23 |
Externally published | Yes |
ASJC Scopus subject areas
- Chemistry(all)
- Chemical Engineering(all)