Tetra-PEG based cell-cartons: Tetra-PEG micro-chamber arrays for cell spheroid formation

H. E. Jeong, Y. J. Heo, Seok Chung, A. Sakuma

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Cell implantation has been garnering attention for the treatment of diverse diseases, including diabetes and cancers. Hydrogel-based scaffolds have been employed for obtaining biocompatible microenvironment and immunoisolation. Many types of cell implantation carriers were presented, but they have yet to be realized ideal cellular environment mainly due to has yet cell leakage problems from unwanted degradation and the low cell viabilities. Here, we develop a cell carton based on mechanically-strong hydrogel, tetra-polyethylene glycol (PEG), and characterize tetra-PEG material properties and potential for cell carriers. We envision that the present cell-spheroids carrier can be a cell implantation platform for cell therapy with less cell-loss and high cell-viability.

Original languageEnglish
Title of host publicationMicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences
PublisherChemical and Biological Microsystems Society
Pages582-584
Number of pages3
ISBN (Electronic)9780979806483
Publication statusPublished - 2015
Event19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2015 - Gyeongju, Korea, Republic of
Duration: 2015 Oct 252015 Oct 29

Other

Other19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2015
CountryKorea, Republic of
CityGyeongju
Period15/10/2515/10/29

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Keywords

  • 3D culture
  • Cell spheroid
  • Cell therapy
  • Tetra-PEG

ASJC Scopus subject areas

  • Control and Systems Engineering

Cite this

Jeong, H. E., Heo, Y. J., Chung, S., & Sakuma, A. (2015). Tetra-PEG based cell-cartons: Tetra-PEG micro-chamber arrays for cell spheroid formation. In MicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences (pp. 582-584). Chemical and Biological Microsystems Society.