Abstract
It is well known that angiogenesis is an essential biological event. To understand fully how the blood vessel grows and functions in the angiogenic process, we should consider the construction of in vivo-like environment, such as three- dimensional (3D) extracellular matrix (ECM). However, most of in vitro studies of the angiogenesis have been relied on two-dimensional (2D) culture or 3D Matrigel culture platforms, which do not account for the in vivo situations. To overcome these limitations in the studies of the angiogenesis, we used a simple microfluidic method incorporating the 3D ECM into the surrounding endothelial cells (ECs) channel.
| Original language | English |
|---|---|
| Title of host publication | 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013 |
| Publisher | Chemical and Biological Microsystems Society |
| Pages | 434-436 |
| Number of pages | 3 |
| Volume | 1 |
| ISBN (Print) | 9781632666246 |
| Publication status | Published - 2013 Jan 1 |
| Event | 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013 - Freiburg, Germany Duration: 2013 Oct 27 → 2013 Oct 31 |
Other
| Other | 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013 |
|---|---|
| Country | Germany |
| City | Freiburg |
| Period | 13/10/27 → 13/10/31 |
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ASJC Scopus subject areas
- Bioengineering
Cite this
The angiogenic sprouting of endothelial cells in three-dimensional collagen gel matrix. / Jeong, Hyo Eun; Seo, Har Rim; Joo, Hyung Joon; Chung, Seok.
17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013. Vol. 1 Chemical and Biological Microsystems Society, 2013. p. 434-436.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - The angiogenic sprouting of endothelial cells in three-dimensional collagen gel matrix
AU - Jeong, Hyo Eun
AU - Seo, Har Rim
AU - Joo, Hyung Joon
AU - Chung, Seok
PY - 2013/1/1
Y1 - 2013/1/1
N2 - It is well known that angiogenesis is an essential biological event. To understand fully how the blood vessel grows and functions in the angiogenic process, we should consider the construction of in vivo-like environment, such as three- dimensional (3D) extracellular matrix (ECM). However, most of in vitro studies of the angiogenesis have been relied on two-dimensional (2D) culture or 3D Matrigel culture platforms, which do not account for the in vivo situations. To overcome these limitations in the studies of the angiogenesis, we used a simple microfluidic method incorporating the 3D ECM into the surrounding endothelial cells (ECs) channel.
AB - It is well known that angiogenesis is an essential biological event. To understand fully how the blood vessel grows and functions in the angiogenic process, we should consider the construction of in vivo-like environment, such as three- dimensional (3D) extracellular matrix (ECM). However, most of in vitro studies of the angiogenesis have been relied on two-dimensional (2D) culture or 3D Matrigel culture platforms, which do not account for the in vivo situations. To overcome these limitations in the studies of the angiogenesis, we used a simple microfluidic method incorporating the 3D ECM into the surrounding endothelial cells (ECs) channel.
KW - Collagen
KW - ECM
KW - Endothelial cells(ECs)
KW - Microfluidics
UR - http://www.scopus.com/inward/record.url?scp=84907313823&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84907313823&partnerID=8YFLogxK
M3 - Conference contribution
AN - SCOPUS:84907313823
SN - 9781632666246
VL - 1
SP - 434
EP - 436
BT - 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
PB - Chemical and Biological Microsystems Society
ER -