The antioxidant properties of solid-culture extracts of basidiomycetous fungi

Jaejung Lee, Joo Hyun Hong, Jeong Do Kim, Jun Ahn Byoung, Beom Seok Kim, Gyu Hyeok Kim, Jae-Jin Kim

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Current studies of the antioxidant activity of fungal resources are mainly focused on the fruiting bodies of edible mushrooms. To access the potential of basidiomycetes in culture-state applications, extracts of solid cultures of 83 basidiomycetous fungi newly isolated from woody materials were prepared at the same concentration (10 mg/ml), and their antioxidant activities were measured using ABTS (2,2′-azino-bis-3-ethylbenzothiazoline-6-sulfonic acid) and DPPH (2,2-diphenyl-1-picrylhydrazyl) radical-scavenging assays. Among the basidiomycetes tested, Cryptoporus volvatus, Daedalea dickinsii, Gloeophyllum abietinum, G. trabeum, Pseudomerulius curtisii and Stereum hirsutum exhibited good antioxidant activities. The EC50 value for the removal of free radicals was lowest (i.e., most effective) in the crude extract of S. sanguinolentum (19.61 g/ml), and reduced DNA damage based on a DNA nicking assay was observed for the extracts from the six basidiomycetous species above.

Original languageEnglish
Pages (from-to)279-285
Number of pages7
JournalJournal of General and Applied Microbiology
Volume59
Issue number4
DOIs
Publication statusPublished - 2013 Sep 13

Fingerprint

Basidiomycota
Fungi
Antioxidants
Mushroom Bodies
Sulfonic Acids
Complex Mixtures
DNA Damage
Free Radicals
DNA
2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acid
2,2-diphenyl-1-picrylhydrazyl

Keywords

  • Antioxidant
  • Basidiomycetes
  • Bioactive metabolites
  • Extracts
  • Radical-scavenging activity

ASJC Scopus subject areas

  • Applied Microbiology and Biotechnology
  • Microbiology

Cite this

The antioxidant properties of solid-culture extracts of basidiomycetous fungi. / Lee, Jaejung; Hong, Joo Hyun; Kim, Jeong Do; Byoung, Jun Ahn; Kim, Beom Seok; Kim, Gyu Hyeok; Kim, Jae-Jin.

In: Journal of General and Applied Microbiology, Vol. 59, No. 4, 13.09.2013, p. 279-285.

Research output: Contribution to journalArticle

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