Abstract
Objective: To study the feasibility of applying the Perclose ProGlide vascular closure device (PPVCD) in vitro for closing a gastrostomy opening for procedural access in the swine stomach in order to prevent peritoneal leakage. Methods: The study included four experimental groups: One manual suture (n = 10), two manual sutures (n = 10), one PPVCD suture (n = 10), and two PPVCD sutures (n = 5). In the two PPVCD sutures group, the "pre-close" technique was used. The leak pressure was measured, and statistical analysis was conducted to compare the leak pressures among the experimental groups. Results: The gastrostomy openings were successfully closed in all experimental groups. The median (range) values of leak pressure (mmHg) for each experimental group were as follows: One manual suture, 86.0 (75.0-110.0); two manual sutures, 98.5 (44.0-130.0); one PPVCD suture, 96.5 (56.0-119.0); and two PPVCD sutures, 98.0 (66.0-104.0). The Mann-Whitney U test revealed no statistically significant difference in leak pressure between the manual (n = 20) and PPVCD (n = 15) suture groups. The Kruskal-Wallis test revealed no statistically significant difference in leak pressure among the four experimental groups. The Bonferroni post hoc test also revealed no statistically significant difference in the pairwise comparisons among the groups. Conclusion: Application of PPVCD is feasible for the closure of gastrostomy openings in an animal model and is as effective as a manual suture. Advances in knowledge: In our in vitro study, percutaneous closure of gastrostomy opening using PPVCD was possible; animal survival studies and development of specific devices are needed before clinical application.
| Original language | English |
|---|---|
| Article number | 92 |
| Journal | British Journal of Radiology |
| Volume | 92 |
| Issue number | 1099 |
| DOIs | |
| Publication status | Published - 2019 Jan 1 |
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ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging
Cite this
The application of a vascular closure device for closing a gastrostomy opening used for procedural access. / Cho, Sung Bum; Kim, Hyoung Rae; Jung, Eui Chul; Chung, Hwan Hoon; Lee, Seung Hwa; Park, Beomjin; Sung, Deuk Jae.
In: British Journal of Radiology, Vol. 92, No. 1099, 92, 01.01.2019.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - The application of a vascular closure device for closing a gastrostomy opening used for procedural access
AU - Cho, Sung Bum
AU - Kim, Hyoung Rae
AU - Jung, Eui Chul
AU - Chung, Hwan Hoon
AU - Lee, Seung Hwa
AU - Park, Beomjin
AU - Sung, Deuk Jae
PY - 2019/1/1
Y1 - 2019/1/1
N2 - Objective: To study the feasibility of applying the Perclose ProGlide vascular closure device (PPVCD) in vitro for closing a gastrostomy opening for procedural access in the swine stomach in order to prevent peritoneal leakage. Methods: The study included four experimental groups: One manual suture (n = 10), two manual sutures (n = 10), one PPVCD suture (n = 10), and two PPVCD sutures (n = 5). In the two PPVCD sutures group, the "pre-close" technique was used. The leak pressure was measured, and statistical analysis was conducted to compare the leak pressures among the experimental groups. Results: The gastrostomy openings were successfully closed in all experimental groups. The median (range) values of leak pressure (mmHg) for each experimental group were as follows: One manual suture, 86.0 (75.0-110.0); two manual sutures, 98.5 (44.0-130.0); one PPVCD suture, 96.5 (56.0-119.0); and two PPVCD sutures, 98.0 (66.0-104.0). The Mann-Whitney U test revealed no statistically significant difference in leak pressure between the manual (n = 20) and PPVCD (n = 15) suture groups. The Kruskal-Wallis test revealed no statistically significant difference in leak pressure among the four experimental groups. The Bonferroni post hoc test also revealed no statistically significant difference in the pairwise comparisons among the groups. Conclusion: Application of PPVCD is feasible for the closure of gastrostomy openings in an animal model and is as effective as a manual suture. Advances in knowledge: In our in vitro study, percutaneous closure of gastrostomy opening using PPVCD was possible; animal survival studies and development of specific devices are needed before clinical application.
AB - Objective: To study the feasibility of applying the Perclose ProGlide vascular closure device (PPVCD) in vitro for closing a gastrostomy opening for procedural access in the swine stomach in order to prevent peritoneal leakage. Methods: The study included four experimental groups: One manual suture (n = 10), two manual sutures (n = 10), one PPVCD suture (n = 10), and two PPVCD sutures (n = 5). In the two PPVCD sutures group, the "pre-close" technique was used. The leak pressure was measured, and statistical analysis was conducted to compare the leak pressures among the experimental groups. Results: The gastrostomy openings were successfully closed in all experimental groups. The median (range) values of leak pressure (mmHg) for each experimental group were as follows: One manual suture, 86.0 (75.0-110.0); two manual sutures, 98.5 (44.0-130.0); one PPVCD suture, 96.5 (56.0-119.0); and two PPVCD sutures, 98.0 (66.0-104.0). The Mann-Whitney U test revealed no statistically significant difference in leak pressure between the manual (n = 20) and PPVCD (n = 15) suture groups. The Kruskal-Wallis test revealed no statistically significant difference in leak pressure among the four experimental groups. The Bonferroni post hoc test also revealed no statistically significant difference in the pairwise comparisons among the groups. Conclusion: Application of PPVCD is feasible for the closure of gastrostomy openings in an animal model and is as effective as a manual suture. Advances in knowledge: In our in vitro study, percutaneous closure of gastrostomy opening using PPVCD was possible; animal survival studies and development of specific devices are needed before clinical application.
UR - http://www.scopus.com/inward/record.url?scp=85068929179&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85068929179&partnerID=8YFLogxK
U2 - 10.1259/bjr.20180837
DO - 10.1259/bjr.20180837
M3 - Article
C2 - 31150282
AN - SCOPUS:85068929179
VL - 92
JO - The British journal of radiology.
JF - The British journal of radiology.
SN - 0007-1285
IS - 1099
M1 - 92
ER -