The association between periodontitis and obstructive sleep apnea

A preliminary study

Won Hee Seo, E. R. Cho, R. J. Thomas, S. Y. An, Jae Jun Ryu, H. Kim, Chol Shin

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Background and Objective: Periodontitis is becoming a highly prevalent disease worldwide. Obstructive sleep apnea (OSA) is a common disorder that is characterized by repeated disruptions in breathing during sleep, and mouth breathing is a common characteristic among patients with OSA. We aimed to assess the hypothesis that OSA is associated with the onset and progression of periodontal disease. Material and Methods: This is a cross-sectional study of a total of 687 participants (460 men and 227 women), 47-77 years of age, who were examined between August 2009 and September 2010 as part of the Korean Genome and Epidemiology Study. The participants underwent standard polysomnography, clinical periodontal examination and health-screening examinations. Periodontitis was defined as clinical attachment level (CAL) ≥ 6 mm and probing pocket depth ≥ 4 mm. OSA was determined using the apnea-hypopnea index (AHI), and an AHI score of ≥ 5 was the cut-off used to indicate the presence of OSA. Results: The results showed that 17.5% of the participants had periodontitis, 46.6% had OSA and 60.0% who were diagnosed with periodontitis had OSA. In our study, old age, male gender, current smoking status, mouth breathing during sleep and high AHI were identified as risk factors for periodontitis. OSA was positively associated with periodontitis [odds ratio (OR) = 1.84, 95% confidence interval (CI) = 1.18-2.87], probing pocket depth (OR = 2.22, 95% CI = 1.30-3.77) and CAL (OR = 1.86, 95% CI = 1.07-3.21) in a dose-response manner. Additionally, OSA was positively associated with periodontitis (OR = 2.51, 95% CI = 1.37-4.62) in subjects ≥ 55 years of age, but not in subjects < 55 years of age. Conclusion: There is a significant association between OSA and periodontal disease. Further research is needed to clarify the causal relationship between the two conditions.

Original languageEnglish
Pages (from-to)500-506
Number of pages7
JournalJournal of Periodontal Research
Volume48
Issue number4
DOIs
Publication statusPublished - 2013 Aug 1

Fingerprint

Periodontitis
Obstructive Sleep Apnea
Odds Ratio
Mouth Breathing
Confidence Intervals
Periodontal Diseases
Apnea
Polysomnography
Sleep Apnea Syndromes
Sleep
Respiration
Epidemiology
Cross-Sectional Studies
Smoking
Genome

Keywords

  • Mouth breathing
  • Obstructive sleep apnea
  • Periodontal disease
  • Periodontitis

ASJC Scopus subject areas

  • Periodontics

Cite this

The association between periodontitis and obstructive sleep apnea : A preliminary study. / Seo, Won Hee; Cho, E. R.; Thomas, R. J.; An, S. Y.; Ryu, Jae Jun; Kim, H.; Shin, Chol.

In: Journal of Periodontal Research, Vol. 48, No. 4, 01.08.2013, p. 500-506.

Research output: Contribution to journalArticle

@article{c7b47beb351d406da27457bb2f5dee65,
title = "The association between periodontitis and obstructive sleep apnea: A preliminary study",
abstract = "Background and Objective: Periodontitis is becoming a highly prevalent disease worldwide. Obstructive sleep apnea (OSA) is a common disorder that is characterized by repeated disruptions in breathing during sleep, and mouth breathing is a common characteristic among patients with OSA. We aimed to assess the hypothesis that OSA is associated with the onset and progression of periodontal disease. Material and Methods: This is a cross-sectional study of a total of 687 participants (460 men and 227 women), 47-77 years of age, who were examined between August 2009 and September 2010 as part of the Korean Genome and Epidemiology Study. The participants underwent standard polysomnography, clinical periodontal examination and health-screening examinations. Periodontitis was defined as clinical attachment level (CAL) ≥ 6 mm and probing pocket depth ≥ 4 mm. OSA was determined using the apnea-hypopnea index (AHI), and an AHI score of ≥ 5 was the cut-off used to indicate the presence of OSA. Results: The results showed that 17.5{\%} of the participants had periodontitis, 46.6{\%} had OSA and 60.0{\%} who were diagnosed with periodontitis had OSA. In our study, old age, male gender, current smoking status, mouth breathing during sleep and high AHI were identified as risk factors for periodontitis. OSA was positively associated with periodontitis [odds ratio (OR) = 1.84, 95{\%} confidence interval (CI) = 1.18-2.87], probing pocket depth (OR = 2.22, 95{\%} CI = 1.30-3.77) and CAL (OR = 1.86, 95{\%} CI = 1.07-3.21) in a dose-response manner. Additionally, OSA was positively associated with periodontitis (OR = 2.51, 95{\%} CI = 1.37-4.62) in subjects ≥ 55 years of age, but not in subjects < 55 years of age. Conclusion: There is a significant association between OSA and periodontal disease. Further research is needed to clarify the causal relationship between the two conditions.",
keywords = "Mouth breathing, Obstructive sleep apnea, Periodontal disease, Periodontitis",
author = "Seo, {Won Hee} and Cho, {E. R.} and Thomas, {R. J.} and An, {S. Y.} and Ryu, {Jae Jun} and H. Kim and Chol Shin",
year = "2013",
month = "8",
day = "1",
doi = "10.1111/jre.12032",
language = "English",
volume = "48",
pages = "500--506",
journal = "Journal of Periodontal Research",
issn = "0022-3484",
publisher = "Blackwell Munksgaard",
number = "4",

}

TY - JOUR

T1 - The association between periodontitis and obstructive sleep apnea

T2 - A preliminary study

AU - Seo, Won Hee

AU - Cho, E. R.

AU - Thomas, R. J.

AU - An, S. Y.

AU - Ryu, Jae Jun

AU - Kim, H.

AU - Shin, Chol

PY - 2013/8/1

Y1 - 2013/8/1

N2 - Background and Objective: Periodontitis is becoming a highly prevalent disease worldwide. Obstructive sleep apnea (OSA) is a common disorder that is characterized by repeated disruptions in breathing during sleep, and mouth breathing is a common characteristic among patients with OSA. We aimed to assess the hypothesis that OSA is associated with the onset and progression of periodontal disease. Material and Methods: This is a cross-sectional study of a total of 687 participants (460 men and 227 women), 47-77 years of age, who were examined between August 2009 and September 2010 as part of the Korean Genome and Epidemiology Study. The participants underwent standard polysomnography, clinical periodontal examination and health-screening examinations. Periodontitis was defined as clinical attachment level (CAL) ≥ 6 mm and probing pocket depth ≥ 4 mm. OSA was determined using the apnea-hypopnea index (AHI), and an AHI score of ≥ 5 was the cut-off used to indicate the presence of OSA. Results: The results showed that 17.5% of the participants had periodontitis, 46.6% had OSA and 60.0% who were diagnosed with periodontitis had OSA. In our study, old age, male gender, current smoking status, mouth breathing during sleep and high AHI were identified as risk factors for periodontitis. OSA was positively associated with periodontitis [odds ratio (OR) = 1.84, 95% confidence interval (CI) = 1.18-2.87], probing pocket depth (OR = 2.22, 95% CI = 1.30-3.77) and CAL (OR = 1.86, 95% CI = 1.07-3.21) in a dose-response manner. Additionally, OSA was positively associated with periodontitis (OR = 2.51, 95% CI = 1.37-4.62) in subjects ≥ 55 years of age, but not in subjects < 55 years of age. Conclusion: There is a significant association between OSA and periodontal disease. Further research is needed to clarify the causal relationship between the two conditions.

AB - Background and Objective: Periodontitis is becoming a highly prevalent disease worldwide. Obstructive sleep apnea (OSA) is a common disorder that is characterized by repeated disruptions in breathing during sleep, and mouth breathing is a common characteristic among patients with OSA. We aimed to assess the hypothesis that OSA is associated with the onset and progression of periodontal disease. Material and Methods: This is a cross-sectional study of a total of 687 participants (460 men and 227 women), 47-77 years of age, who were examined between August 2009 and September 2010 as part of the Korean Genome and Epidemiology Study. The participants underwent standard polysomnography, clinical periodontal examination and health-screening examinations. Periodontitis was defined as clinical attachment level (CAL) ≥ 6 mm and probing pocket depth ≥ 4 mm. OSA was determined using the apnea-hypopnea index (AHI), and an AHI score of ≥ 5 was the cut-off used to indicate the presence of OSA. Results: The results showed that 17.5% of the participants had periodontitis, 46.6% had OSA and 60.0% who were diagnosed with periodontitis had OSA. In our study, old age, male gender, current smoking status, mouth breathing during sleep and high AHI were identified as risk factors for periodontitis. OSA was positively associated with periodontitis [odds ratio (OR) = 1.84, 95% confidence interval (CI) = 1.18-2.87], probing pocket depth (OR = 2.22, 95% CI = 1.30-3.77) and CAL (OR = 1.86, 95% CI = 1.07-3.21) in a dose-response manner. Additionally, OSA was positively associated with periodontitis (OR = 2.51, 95% CI = 1.37-4.62) in subjects ≥ 55 years of age, but not in subjects < 55 years of age. Conclusion: There is a significant association between OSA and periodontal disease. Further research is needed to clarify the causal relationship between the two conditions.

KW - Mouth breathing

KW - Obstructive sleep apnea

KW - Periodontal disease

KW - Periodontitis

UR - http://www.scopus.com/inward/record.url?scp=84879460597&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84879460597&partnerID=8YFLogxK

U2 - 10.1111/jre.12032

DO - 10.1111/jre.12032

M3 - Article

VL - 48

SP - 500

EP - 506

JO - Journal of Periodontal Research

JF - Journal of Periodontal Research

SN - 0022-3484

IS - 4

ER -