The association between serum 25-hydroxyvitamin D concentrations and depressive symptoms in Korean adults: Findings from the fifth Korea National Health and Nutrition Examination Survey 2010

Hye Kyung Chung, Yoonsu Cho, Sumi Choi, Min-Jeong Shin

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15 Citations (Scopus)

Abstract

The aims of this study were to examine the association between circulating vitamin D (25(OH)D) levels and depressive symptoms and to evaluate the associations between depressive symptoms and various sociodemographic factors. Data on serum 25(OH)D levels, sociodemographic factors, and information on depressive symptoms were obtained from the Korea National Health and Nutrition Examination Survey V-1 2010. A total of 3,570 Koreans aged ≥20 years were included in the statistical analysis. Subjects with depressive symptoms had lower serum levels of 25(OH)D (41.6±16.2 nmol/L) than those without (44.3±16.2 nmol/L; P-value<0.05; effect size = 0.17). In a logistic regression analysis, the 25(OH)D sufficiency group (≥50 nmol/L) revealed fewer depressive symptoms (OR, 0.72; 95% CI, 0.53-0.97; P-value = 0.032) after adjusting for multiple factors. In addition, females (OR, 3.61; 95% CI, 2.55-5.11; P-value<0.001), problematic alcohol users (OR, 2.33; 95% CI, 1.63-3.34; P-value<0.001), current smokers (OR, 1.43; 95% CI, 1.02-1.99; P-value = 0.036), and subjects who experienced weight loss (OR, 1.78; 95% CI, 1.30-2.44; P-value<0.001) were more likely to answer "yes" on question for depressive symptoms. In conclusion, low serum levels of 25(OH)D were associated with an increased risk for depression symptoms in Korean adults. In addition, several sociodemographic factors were related to the depressive symptoms. Our results provide insight into the relationships among vitamin D status, sociodemographic factors, and depression in the Korean population. Copyright:

Original languageEnglish
Article numbere99185
JournalPLoS One
Volume9
Issue number6
DOIs
Publication statusPublished - 2014 Jun 19

Fingerprint

National Health and Nutrition Examination Survey
Nutrition Surveys
Korea
Nutrition
vitamin D
Vitamin D
Korean Peninsula
Health
Depression
Serum
Regression analysis
Logistics
Statistical methods
regression analysis
statistical analysis
weight loss
alcohols
Alcohols
25-hydroxyvitamin D
Weight Loss

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Medicine(all)

Cite this

@article{428c9fa255294b0ca6ba72500444d310,
title = "The association between serum 25-hydroxyvitamin D concentrations and depressive symptoms in Korean adults: Findings from the fifth Korea National Health and Nutrition Examination Survey 2010",
abstract = "The aims of this study were to examine the association between circulating vitamin D (25(OH)D) levels and depressive symptoms and to evaluate the associations between depressive symptoms and various sociodemographic factors. Data on serum 25(OH)D levels, sociodemographic factors, and information on depressive symptoms were obtained from the Korea National Health and Nutrition Examination Survey V-1 2010. A total of 3,570 Koreans aged ≥20 years were included in the statistical analysis. Subjects with depressive symptoms had lower serum levels of 25(OH)D (41.6±16.2 nmol/L) than those without (44.3±16.2 nmol/L; P-value<0.05; effect size = 0.17). In a logistic regression analysis, the 25(OH)D sufficiency group (≥50 nmol/L) revealed fewer depressive symptoms (OR, 0.72; 95{\%} CI, 0.53-0.97; P-value = 0.032) after adjusting for multiple factors. In addition, females (OR, 3.61; 95{\%} CI, 2.55-5.11; P-value<0.001), problematic alcohol users (OR, 2.33; 95{\%} CI, 1.63-3.34; P-value<0.001), current smokers (OR, 1.43; 95{\%} CI, 1.02-1.99; P-value = 0.036), and subjects who experienced weight loss (OR, 1.78; 95{\%} CI, 1.30-2.44; P-value<0.001) were more likely to answer {"}yes{"} on question for depressive symptoms. In conclusion, low serum levels of 25(OH)D were associated with an increased risk for depression symptoms in Korean adults. In addition, several sociodemographic factors were related to the depressive symptoms. Our results provide insight into the relationships among vitamin D status, sociodemographic factors, and depression in the Korean population. Copyright:",
author = "Chung, {Hye Kyung} and Yoonsu Cho and Sumi Choi and Min-Jeong Shin",
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