TY - JOUR
T1 - The association of Sasang constitutional types with metabolic syndrome
T2 - A pooled analysis of data from three cohorts
AU - Lee, Seung Ku
AU - Yoon, Dae Wui
AU - Choi, Kyung Mee
AU - Lee, Si Woo
AU - Kim, Jong Yeol
AU - Kim, Jin Kwan
AU - Hong, Jeong Hwa
AU - Cho, Nam Han
AU - Shin, Chol
N1 - Funding Information:
This research was supported by the Bio & Medical Technology Development Program of the National Research Foundation (NRF) funded by the Ministry of Science, ICT & Future Planning (Nos. 2012-0009830, 2006-2005173), and by a fund (2009-E71002-00, 2009-E71007-00, 2010-E71001-00, 2010-E71004-00, 2011-E71004-00, 2011-E71008-00) for research from the Korea Centers for Disease Control and Prevention and supported by a Korea University Grant.
Publisher Copyright:
© 2016
PY - 2016/6/1
Y1 - 2016/6/1
N2 - Introduction Metabolic syndrome (MetS) is a highly prevalent condition, which is considered to be a major risk factor for cardiovascular diseases. Sasang constitutional types (SCTs) are divided into four distinct types which are classified by specific physical, physiological, pharmacological, and psychological characteristics. Methods In this study, we performed a pooled analysis to assess the relationship between MetS and SCTs using data from two community-based cohorts and one clinical database of Sasang constitution. The 1421, 1547, and 2279 individuals who participated in the Ansung cohort, Ansan cohort, and Korean Constitutional Multicenter Bank, respectively, were analyzed. The participants were classified into SCTs using the integrated diagnostic model. MetS was defined according to the National Cholesterol Education Program Adult Treatment Panel III. Results The prevalence of MetS according to the SCTs in the combined data was 14.1% for the So-eum (SE)-type, 26.7% for the So-yang (SY)-type, and 50.8% for the Tae-eum (TE)-type. In the combined data set, the odds ratios of having MetS was 2.05-fold greater (95% confidence interval [CI], 1.62–2.60; P < 0.0001) for the TE-type, and 1.41-fold greater (95% CI, 1.13–1.76; P = 0.0026) for the SY-type than the SE-type. Conclusions This study found that TE- and SY-types were significantly associated with a risk of MetS.
AB - Introduction Metabolic syndrome (MetS) is a highly prevalent condition, which is considered to be a major risk factor for cardiovascular diseases. Sasang constitutional types (SCTs) are divided into four distinct types which are classified by specific physical, physiological, pharmacological, and psychological characteristics. Methods In this study, we performed a pooled analysis to assess the relationship between MetS and SCTs using data from two community-based cohorts and one clinical database of Sasang constitution. The 1421, 1547, and 2279 individuals who participated in the Ansung cohort, Ansan cohort, and Korean Constitutional Multicenter Bank, respectively, were analyzed. The participants were classified into SCTs using the integrated diagnostic model. MetS was defined according to the National Cholesterol Education Program Adult Treatment Panel III. Results The prevalence of MetS according to the SCTs in the combined data was 14.1% for the So-eum (SE)-type, 26.7% for the So-yang (SY)-type, and 50.8% for the Tae-eum (TE)-type. In the combined data set, the odds ratios of having MetS was 2.05-fold greater (95% confidence interval [CI], 1.62–2.60; P < 0.0001) for the TE-type, and 1.41-fold greater (95% CI, 1.13–1.76; P = 0.0026) for the SY-type than the SE-type. Conclusions This study found that TE- and SY-types were significantly associated with a risk of MetS.
KW - Cohort analysis
KW - Metabolic syndrome
KW - Sasang constitutional types
KW - So-eum
KW - So-yang
KW - Tae-eum
UR - http://www.scopus.com/inward/record.url?scp=84964370851&partnerID=8YFLogxK
U2 - 10.1016/j.eujim.2015.11.017
DO - 10.1016/j.eujim.2015.11.017
M3 - Article
AN - SCOPUS:84964370851
VL - 8
SP - 227
EP - 234
JO - European Journal of Integrative Medicine
JF - European Journal of Integrative Medicine
SN - 1876-3820
IS - 3
ER -
