The clinical profile of patients with psoriasis in Korea: A nationwide cross-sectional study (EPI-PSODE)

Hae Jun Song, Chul Jong Park, Tae Yoon Kim, Yong Beom Choe, Seok Jong Lee, Nack In Kim, Jae We Cho, Jie Hyun Jeon, Min Soo Jang, Jai Il Youn, Myung Hwa Kim, Joonsoo Park, Ki Ho Kim, Byung Soo Kim, Sang Woong Youn, Joo Heung Lee, Min Geol Lee, Sung Ku Ahn, Young Ho Won, Seok Kweon YunBong Seok Shin, Seong Jun Seo, Ji Yeoun Lee, Kwang Joong Kim, Young Suck Ro, Youngdoe Kim, Dae Young Yu, Jee Ho Choi

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Background: Psoriasis is an immune-mediated, chronic inflammatory disease affecting multiple aspects of patients' lives. Its epidemiology varies regionally; however, nationwide epidemiologic data on psoriasis depicting profile of Korean patients has not been available to date. Objective: To understand nationwide epidemiologic characteristics and clinical features of adult patients with psoriasis visited university hospitals in Korea. Methods: This multicenter, non-interventional, cross-sectional study recruited 1,278 adult patients with psoriasis across 25 centers in Korea in 2013. Various clinical data including PASI, BSA, DLQI, SF-36 and PASE were collected. Results: A total of 1,260 patients completed the study (male:female=1.47:1). The mean age was 47.0 years with a distribution mostly in the 50s (24.9%). Early onset (40 years) of psoriasis accounted for 53.9% of patients. The mean disease duration was 109.2 months; mean body mass index was 23.9 kg/m2; and 12.7% of patients had a family history of psoriasis. Plaque and guttate types of psoriasis accounted for 85.8% and 8.4%, respectively. Patients with PASI ≥10 accounted for 24.9%; patients with body surface area ≥10 were 45.9%. Patients with DLQI ≥6 accounted for 78.8%. Between PASI 10 and PASI ≥10 groups, significant difference was noted in age at diagnosis, disease duration, blood pressure, waist circumference of female, and treatment experiences with phototherapy, systemic agents, and biologics. Conclusion: This was the first nationwide epidemiologic study of patients with psoriasis in Korea and provides an overview of the epidemio logic characteristics and clinical profiles of this patient population. (Ann Dermatol 29(4) 462∼470, 2017).

Original languageEnglish
Pages (from-to)462-470
Number of pages9
JournalAnnals of Dermatology
Volume29
Issue number4
DOIs
Publication statusPublished - 2017 Aug

Keywords

  • Epidemiologic studies
  • Korea
  • Psoriasis

ASJC Scopus subject areas

  • Dermatology

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