@article{678fe173c7204cec859b2bbd3ef1686e,
title = "The discovery of penta-peptides inhibiting the activity of the formylglycine-generating enzyme and their potential antibacterial effects against Mycobacterium tuberculosis",
abstract = "The formylglycine-generating enzyme is a key regulator that converts sulfatase into an active form. Despite its key role in many diseases, enzyme activity inhibitors have not yet been reported. In this study, we investigated penta-peptide ligands for FGE activity inhibition and discovered two hit peptides. In addition, the lead peptides also showed potential antibacterial effects in a Mycobacterium tuberculosis model.",
author = "Nicholas Asiimwe and {Al Mazid}, {Mohammad Faysal} and Jeong, {Yong Taek} and Juyong Lee and Jun-Seok Lee",
note = "Funding Information: This work is supported by a Korea University Guro Hospital (KOREA RESEARCH-DRIVEN HOSPITAL) grant funded by Korea University Medicine (K2210341), Korea University Grant (K2110571), and the National Research Foundation (NRF-2018M3A9H4079286 and NRF-2020R1A2C2004422). Publisher Copyright: {\textcopyright} 2022 The Royal Society of Chemistry",
year = "2022",
month = jun,
day = "29",
doi = "10.1039/d2ra03379h",
language = "English",
volume = "12",
pages = "18884--18888",
journal = "RSC Advances",
issn = "2046-2069",
publisher = "Royal Society of Chemistry",
number = "29",
}
