The effect of bio-converted polyunsaturated fatty acids on the oxidation of TAG containing highly unsaturated fatty acids

Young Mi Kim, Geon Ho Lee, Young Geun Yeo, In-Hwan Kim, Kazuo Miyashita, Ching T. Hou, Sun Chul Kang, Hak Ryul Kim

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4 Citations (Scopus)


Microbial modification of vegetable fatty acids can often lead to special changes in their structure and in biological function. A bacterial strain, Pseudomonas aeruginosa PR3, is known to carry out multiple hydroxylations on polyunsaturated fatty acids containing 1,4-cis, cis diene structural units, resulting in antibacterial activity. In this paper, in an effort to understand the overall mechanism involved in the varied biological functions of the complicated metabolites of bio-converted polyunsaturated fatty acids, we performed bioconversion of several polyunsaturated fatty acids using PR3, and determined their oxidative activities against fish oil. Bio-converted linoleic acid, eicosapentanoic acid, and docosahexanoic acid promoted effectively oxidation of fish oil. It is assumed that this oxidative effect could plausibly play an important role in the antimicrobial function of these bio-converted fatty acids.

Original languageEnglish
Pages (from-to)17-21
Number of pages5
JournalJournal of Industrial Microbiology and Biotechnology
Issue number1
Publication statusPublished - 2006 Jan 1



  • Bio-conversion
  • Hydroxy fatty acid
  • Oxidation
  • Pseudomonas aeruginosa

ASJC Scopus subject areas

  • Biotechnology
  • Applied Microbiology and Biotechnology
  • Microbiology
  • Bioengineering

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