The Effect of Fluid Viscosity on the Hemodynamic Energy Changes During Operation of the Pulsatile Ventricular Assist Device

Chi Bum Ahn, Kuk Hui Son, Jung Joo Lee, Jaesoon Choi, Seung Joon Song, Jae Seung Jung, Sung Ho Lee, Ho Sung Son, Kyung Sun

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Blood viscosity during operation of ventricular assist device (VAD) can be changed by various conditions such as anemia. It is known generally that the blood viscosity can affect vascular resistance and lead to change of blood flow. In this study, the effect of fluid viscosity variation on hemodynamic energy was evaluated with a pulsatile blood pump in a mock system. Six solutions were used for experiments, which were composed of water and glycerin and had different viscosities of 2, 2.5, 3, 3.5, 4, and 4.5cP. The hemodynamic energy at the outlet cannula was measured. Experimental results showed that mean pressure was increased in accordance with the viscosity increase. When the viscosity increased, the mean pressure was also increased. However, the flow was decreased according to the viscosity increase. Energy equivalent pressure value was increased according to the viscosity-induced pressure rise; however, surplus hemodynamic energy value did not show any apparent changing trend. The hemodynamic energy made by the pulsatile VAD was affected by the viscosity of the circulating fluid.

Original languageEnglish
Pages (from-to)1123-1126
Number of pages4
JournalArtificial Organs
Volume35
Issue number11
DOIs
Publication statusPublished - 2011 Nov

Keywords

  • Energy equivalent pressure
  • Hemodynamic energy
  • Pulsatility
  • Surplus hemodynamic energy
  • Viscosity

ASJC Scopus subject areas

  • Bioengineering
  • Medicine (miscellaneous)
  • Biomaterials
  • Biomedical Engineering

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