The efficacy of stereoimage optical topometry to evaluate depressed acne scar treatment using cultured autologous fibroblast injection

Jeong Eun Kim, On Seok Lee, Jaydo Choi, Sang Wook Son, Chil Hwan Oh

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

BACKGROUND Despite the use of several evaluation methods, the lack of a true consensus scale hinders standardization of evaluation and treatment of depressed acne scars. OBJECTIVE To investigate the usefulness of a stereoimage optical topometer (SOT) system in evaluating the efficacy of autologous cultured fibroblast injection for depressed acne scars and to compare the results with those obtained using a visual grading system. MATERIALS AND METHODS Twenty-two patients with depressed acne scars were included. Three doses of cultured autologous fibroblast (2 × 10 7 cell/mL) injections were given at 2-week intervals. Efficacy was evaluated at 2, 4, 12, and 16 weeks using a visual grading system and a SOT. RESULTS After autologous fibroblast injection, the lesions evaluated using the visual grading and SOT systems steadily improved. Visual grading and SOT variables obtained showed a similar tendency, although an interrater reliability test of the visual grading system correlated poorly. CONCLUSIONS A three-dimensional morphologic study can be a useful and reliable method of evaluating the severity of acne scars. We were able to more objectively and quantitatively evaluate acne scar severity through combined analysis using visual grading and SOT systems.

Original languageEnglish
Pages (from-to)1304-1313
Number of pages10
JournalDermatologic Surgery
Volume37
Issue number9
DOIs
Publication statusPublished - 2011 Sep 1

Fingerprint

Acne Vulgaris
Cicatrix
Fibroblasts
Optical Devices
Injections
Therapeutics

ASJC Scopus subject areas

  • Dermatology
  • Surgery

Cite this

The efficacy of stereoimage optical topometry to evaluate depressed acne scar treatment using cultured autologous fibroblast injection. / Kim, Jeong Eun; Lee, On Seok; Choi, Jaydo; Son, Sang Wook; Oh, Chil Hwan.

In: Dermatologic Surgery, Vol. 37, No. 9, 01.09.2011, p. 1304-1313.

Research output: Contribution to journalArticle

@article{80ac672c552f4a62a15342882d23a3e0,
title = "The efficacy of stereoimage optical topometry to evaluate depressed acne scar treatment using cultured autologous fibroblast injection",
abstract = "BACKGROUND Despite the use of several evaluation methods, the lack of a true consensus scale hinders standardization of evaluation and treatment of depressed acne scars. OBJECTIVE To investigate the usefulness of a stereoimage optical topometer (SOT) system in evaluating the efficacy of autologous cultured fibroblast injection for depressed acne scars and to compare the results with those obtained using a visual grading system. MATERIALS AND METHODS Twenty-two patients with depressed acne scars were included. Three doses of cultured autologous fibroblast (2 × 10 7 cell/mL) injections were given at 2-week intervals. Efficacy was evaluated at 2, 4, 12, and 16 weeks using a visual grading system and a SOT. RESULTS After autologous fibroblast injection, the lesions evaluated using the visual grading and SOT systems steadily improved. Visual grading and SOT variables obtained showed a similar tendency, although an interrater reliability test of the visual grading system correlated poorly. CONCLUSIONS A three-dimensional morphologic study can be a useful and reliable method of evaluating the severity of acne scars. We were able to more objectively and quantitatively evaluate acne scar severity through combined analysis using visual grading and SOT systems.",
author = "Kim, {Jeong Eun} and Lee, {On Seok} and Jaydo Choi and Son, {Sang Wook} and Oh, {Chil Hwan}",
year = "2011",
month = "9",
day = "1",
doi = "10.1111/j.1524-4725.2011.02046.x",
language = "English",
volume = "37",
pages = "1304--1313",
journal = "Dermatologic Surgery",
issn = "1076-0512",
publisher = "Wiley-Blackwell",
number = "9",

}

TY - JOUR

T1 - The efficacy of stereoimage optical topometry to evaluate depressed acne scar treatment using cultured autologous fibroblast injection

AU - Kim, Jeong Eun

AU - Lee, On Seok

AU - Choi, Jaydo

AU - Son, Sang Wook

AU - Oh, Chil Hwan

PY - 2011/9/1

Y1 - 2011/9/1

N2 - BACKGROUND Despite the use of several evaluation methods, the lack of a true consensus scale hinders standardization of evaluation and treatment of depressed acne scars. OBJECTIVE To investigate the usefulness of a stereoimage optical topometer (SOT) system in evaluating the efficacy of autologous cultured fibroblast injection for depressed acne scars and to compare the results with those obtained using a visual grading system. MATERIALS AND METHODS Twenty-two patients with depressed acne scars were included. Three doses of cultured autologous fibroblast (2 × 10 7 cell/mL) injections were given at 2-week intervals. Efficacy was evaluated at 2, 4, 12, and 16 weeks using a visual grading system and a SOT. RESULTS After autologous fibroblast injection, the lesions evaluated using the visual grading and SOT systems steadily improved. Visual grading and SOT variables obtained showed a similar tendency, although an interrater reliability test of the visual grading system correlated poorly. CONCLUSIONS A three-dimensional morphologic study can be a useful and reliable method of evaluating the severity of acne scars. We were able to more objectively and quantitatively evaluate acne scar severity through combined analysis using visual grading and SOT systems.

AB - BACKGROUND Despite the use of several evaluation methods, the lack of a true consensus scale hinders standardization of evaluation and treatment of depressed acne scars. OBJECTIVE To investigate the usefulness of a stereoimage optical topometer (SOT) system in evaluating the efficacy of autologous cultured fibroblast injection for depressed acne scars and to compare the results with those obtained using a visual grading system. MATERIALS AND METHODS Twenty-two patients with depressed acne scars were included. Three doses of cultured autologous fibroblast (2 × 10 7 cell/mL) injections were given at 2-week intervals. Efficacy was evaluated at 2, 4, 12, and 16 weeks using a visual grading system and a SOT. RESULTS After autologous fibroblast injection, the lesions evaluated using the visual grading and SOT systems steadily improved. Visual grading and SOT variables obtained showed a similar tendency, although an interrater reliability test of the visual grading system correlated poorly. CONCLUSIONS A three-dimensional morphologic study can be a useful and reliable method of evaluating the severity of acne scars. We were able to more objectively and quantitatively evaluate acne scar severity through combined analysis using visual grading and SOT systems.

UR - http://www.scopus.com/inward/record.url?scp=80052335444&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=80052335444&partnerID=8YFLogxK

U2 - 10.1111/j.1524-4725.2011.02046.x

DO - 10.1111/j.1524-4725.2011.02046.x

M3 - Article

C2 - 21631637

AN - SCOPUS:80052335444

VL - 37

SP - 1304

EP - 1313

JO - Dermatologic Surgery

JF - Dermatologic Surgery

SN - 1076-0512

IS - 9

ER -