The efficient one-step chlorination of methylsulfanyl group on pyrimidine ring system with sulfuryl chloride

Young Jin Ham, Duck Hyung Lee, Hwan Geun Choi, Jung M. Hah, Taebo Sim

Research output: Contribution to journalArticle


A facile one-step transformation of methylsulfanyl and arylsulfanyl groups on pyrimidine ring system into the corresponding chloride group was achieved using sulfuryl chloride in acetonitrile/dichloromethane.

Original languageEnglish
Pages (from-to)4609-4611
Number of pages3
JournalTetrahedron Letters
Issue number35
Publication statusPublished - 2010 Sep 1


ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

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