The efficient one-step chlorination of methylsulfanyl group on pyrimidine ring system with sulfuryl chloride

Young Jin Ham, Duck Hyung Lee, Hwan Geun Choi, Jung M. Hah, Taebo Sim

Research output: Contribution to journalArticle

Abstract

A facile one-step transformation of methylsulfanyl and arylsulfanyl groups on pyrimidine ring system into the corresponding chloride group was achieved using sulfuryl chloride in acetonitrile/dichloromethane.

Original languageEnglish
Pages (from-to)4609-4611
Number of pages3
JournalTetrahedron Letters
Volume51
Issue number35
DOIs
Publication statusPublished - 2010 Sep 1

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Chlorination
Halogenation
Chlorides
Methylene Chloride
pyrimidine
acetonitrile

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

The efficient one-step chlorination of methylsulfanyl group on pyrimidine ring system with sulfuryl chloride. / Ham, Young Jin; Lee, Duck Hyung; Choi, Hwan Geun; Hah, Jung M.; Sim, Taebo.

In: Tetrahedron Letters, Vol. 51, No. 35, 01.09.2010, p. 4609-4611.

Research output: Contribution to journalArticle

Ham, Young Jin ; Lee, Duck Hyung ; Choi, Hwan Geun ; Hah, Jung M. ; Sim, Taebo. / The efficient one-step chlorination of methylsulfanyl group on pyrimidine ring system with sulfuryl chloride. In: Tetrahedron Letters. 2010 ; Vol. 51, No. 35. pp. 4609-4611.
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