The iScore predicts functional outcome in korean patients with ischemic stroke

Tai Hwan Park, Gustavo Saposnik, Hee Joon Bae, Soo Joo Lee, Kyung Bok Lee, Jun Lee, Jong Moo Park, Jay Chol Choi, Dong Eog Kim, Yong Jin Cho, Joon Tae Kim, Jae Kwan Cha, Juneyoung Lee, Kyung Ho Yu, Byung Chul Lee, Byung Woo Yoon

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

BACKGROUND AND PURPOSE-: Several stroke risk scores for prediction of functional outcome have been developed, but rarely validated in Asian populations. We assessed the validity of the iScore, recently developed from Canadian stroke population, in an Asian stroke population from Korea. METHODS-: We applied the iScore to 4061 eligible participants with acute ischemic stroke in the nationwide multicenter stroke registry in Korea. The main outcome was poor functional outcome defined as having a modified Rankin Scale 3 to 6 at 3 months after stroke onset. The secondary outcome was death at 3 months. C-statistics were calculated to assess performance of the iScore. RESULTS-: Poor functional outcome was found in 1496 patients (36.8%), whereas death at 3 months occurred in 294 patients (7.2%). C-statistics were 0.819 (95% confidence interval, 0.805-0.833) for poor functional outcome and 0.861 (95% confidence interval, 0.840-0.883) for death. Overall, there was a high correlation between observed and expected outcomes for poor functional outcome (Pearson correlation coefficient, r=0.990) and for death (r=0.969) according to risk score. CONCLUSIONS-: The iScore reliably predicts poor functional outcome or death at 3 months after stroke in Korean patients.

Original languageEnglish
Pages (from-to)1440-1442
Number of pages3
JournalStroke
Volume44
Issue number5
DOIs
Publication statusPublished - 2013 May 1

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Stroke
Korea
Confidence Intervals
Population
Registries

Keywords

  • ischemic stroke
  • outcome
  • prediction
  • risk score

ASJC Scopus subject areas

  • Clinical Neurology
  • Cardiology and Cardiovascular Medicine
  • Advanced and Specialised Nursing

Cite this

Park, T. H., Saposnik, G., Bae, H. J., Lee, S. J., Lee, K. B., Lee, J., ... Yoon, B. W. (2013). The iScore predicts functional outcome in korean patients with ischemic stroke. Stroke, 44(5), 1440-1442. https://doi.org/10.1161/STROKEAHA.111.000748

The iScore predicts functional outcome in korean patients with ischemic stroke. / Park, Tai Hwan; Saposnik, Gustavo; Bae, Hee Joon; Lee, Soo Joo; Lee, Kyung Bok; Lee, Jun; Park, Jong Moo; Choi, Jay Chol; Kim, Dong Eog; Cho, Yong Jin; Kim, Joon Tae; Cha, Jae Kwan; Lee, Juneyoung; Yu, Kyung Ho; Lee, Byung Chul; Yoon, Byung Woo.

In: Stroke, Vol. 44, No. 5, 01.05.2013, p. 1440-1442.

Research output: Contribution to journalArticle

Park, TH, Saposnik, G, Bae, HJ, Lee, SJ, Lee, KB, Lee, J, Park, JM, Choi, JC, Kim, DE, Cho, YJ, Kim, JT, Cha, JK, Lee, J, Yu, KH, Lee, BC & Yoon, BW 2013, 'The iScore predicts functional outcome in korean patients with ischemic stroke', Stroke, vol. 44, no. 5, pp. 1440-1442. https://doi.org/10.1161/STROKEAHA.111.000748
Park TH, Saposnik G, Bae HJ, Lee SJ, Lee KB, Lee J et al. The iScore predicts functional outcome in korean patients with ischemic stroke. Stroke. 2013 May 1;44(5):1440-1442. https://doi.org/10.1161/STROKEAHA.111.000748
Park, Tai Hwan ; Saposnik, Gustavo ; Bae, Hee Joon ; Lee, Soo Joo ; Lee, Kyung Bok ; Lee, Jun ; Park, Jong Moo ; Choi, Jay Chol ; Kim, Dong Eog ; Cho, Yong Jin ; Kim, Joon Tae ; Cha, Jae Kwan ; Lee, Juneyoung ; Yu, Kyung Ho ; Lee, Byung Chul ; Yoon, Byung Woo. / The iScore predicts functional outcome in korean patients with ischemic stroke. In: Stroke. 2013 ; Vol. 44, No. 5. pp. 1440-1442.
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abstract = "BACKGROUND AND PURPOSE-: Several stroke risk scores for prediction of functional outcome have been developed, but rarely validated in Asian populations. We assessed the validity of the iScore, recently developed from Canadian stroke population, in an Asian stroke population from Korea. METHODS-: We applied the iScore to 4061 eligible participants with acute ischemic stroke in the nationwide multicenter stroke registry in Korea. The main outcome was poor functional outcome defined as having a modified Rankin Scale 3 to 6 at 3 months after stroke onset. The secondary outcome was death at 3 months. C-statistics were calculated to assess performance of the iScore. RESULTS-: Poor functional outcome was found in 1496 patients (36.8{\%}), whereas death at 3 months occurred in 294 patients (7.2{\%}). C-statistics were 0.819 (95{\%} confidence interval, 0.805-0.833) for poor functional outcome and 0.861 (95{\%} confidence interval, 0.840-0.883) for death. Overall, there was a high correlation between observed and expected outcomes for poor functional outcome (Pearson correlation coefficient, r=0.990) and for death (r=0.969) according to risk score. CONCLUSIONS-: The iScore reliably predicts poor functional outcome or death at 3 months after stroke in Korean patients.",
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