The mechanism of and preventive therapy for stroke in patients with atrial fibrillation

Young Hoon Kim; Seung Young Roh

doi:10.5853/jos.2016.00234

The mechanism of and preventive therapy for stroke in patients with atrial fibrillation

Young Hoon Kim, Seung Young Roh

Department of Cardiology

Research output: Contribution to journal › Review article › peer-review

12 Citations (Scopus)

Abstract

Atrial fibrillation is a major cardiac cause of stroke, and a pathogenesis involving thrombus formation in patients with atrial fibrillation is well established. A strategy for rhythm control that involves catheter ablation and anticoagulation therapy is evolving. A strategy for rhythm control that restores and maintains sinus rhythm should reduce the risk of ischemic stroke that is associated with atrial fibrillation; however, this is yet to be proven in large-scale randomized controlled trials. This paper reviews the emerging role of rhythm control therapy for atrial fibrillation to prevent stroke.

Original language	English
Pages (from-to)	129-137
Number of pages	9
Journal	Journal of Stroke
Volume	18
Issue number	2
DOIs	https://doi.org/10.5853/jos.2016.00234
Publication status	Published - 2016 May

Keywords

Atrial fibrillation
Catheter ablation
Ischemic stroke
Rhythm control
Thromboembolism

ASJC Scopus subject areas

Clinical Neurology
Cardiology and Cardiovascular Medicine

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AB - Atrial fibrillation is a major cardiac cause of stroke, and a pathogenesis involving thrombus formation in patients with atrial fibrillation is well established. A strategy for rhythm control that involves catheter ablation and anticoagulation therapy is evolving. A strategy for rhythm control that restores and maintains sinus rhythm should reduce the risk of ischemic stroke that is associated with atrial fibrillation; however, this is yet to be proven in large-scale randomized controlled trials. This paper reviews the emerging role of rhythm control therapy for atrial fibrillation to prevent stroke.

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