The neural substrates of affective face recognition in patients with Hwa-Byung and healthy individuals in Korea

Byeong Taek Lee, Jong Woo Paik, Rhee Hun Kang, Sun Yong Chung, Ho In Kwon, Hyun Soo Khang, In Kyoon Lyoo, Jeong Ho Chae, Jung Hye Kwon, Jong Woo Kim, Min-Soo Lee, Byung-Joo Ham

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Hwa-Byung (HB) is a Korean culture-bound psychiatric syndrome caused by the suppression of anger. HB patients have various psychological and somatic symptoms, such as chest discomfort, a sensation of heat, and the sensation of having an epigastric mass. In this study, we measured brain activity in HB patients and healthy individuals in response to affective facial stimuli. Using functional magnetic resonance imaging (fMRI), the current study measured neural responses to neutral, sad, and angry facial stimuli in 12 healthy individuals and 12 patients with HB. In response to all types of facial stimuli, HB patients showed increased activations in the lingual gyrus and fusiform gyrus compared with healthy persons, but they showed relatively lower activation in the thalamus. We also found that patients with HB showed lower activity in response to the neutral condition in the right ACC than healthy controls. The current study indicates that the suppression of affect results in aberrant function of the brain regions of the visual pathway, and functional impairment in the ACC may contribute to the pathophysiology of HB.

Original languageEnglish
Pages (from-to)552-559
Number of pages8
JournalWorld Journal of Biological Psychiatry
Volume10
Issue number4 PART 2
DOIs
Publication statusPublished - 2009 Dec 1

Fingerprint

Korea
Occipital Lobe
Visual Pathways
Anger
Brain
Temporal Lobe
Thalamus
Psychiatry
Thorax
Hot Temperature
Magnetic Resonance Imaging
Facial Recognition
Psychology

Keywords

  • Anger
  • Functional magnetic resonance imaging (fMRI)
  • Hwa-Byung
  • Sad
  • Visual pathway

ASJC Scopus subject areas

  • Biological Psychiatry
  • Psychiatry and Mental health
  • Medicine(all)

Cite this

The neural substrates of affective face recognition in patients with Hwa-Byung and healthy individuals in Korea. / Lee, Byeong Taek; Paik, Jong Woo; Kang, Rhee Hun; Chung, Sun Yong; Kwon, Ho In; Khang, Hyun Soo; Lyoo, In Kyoon; Chae, Jeong Ho; Kwon, Jung Hye; Kim, Jong Woo; Lee, Min-Soo; Ham, Byung-Joo.

In: World Journal of Biological Psychiatry, Vol. 10, No. 4 PART 2, 01.12.2009, p. 552-559.

Research output: Contribution to journalArticle

Lee, BT, Paik, JW, Kang, RH, Chung, SY, Kwon, HI, Khang, HS, Lyoo, IK, Chae, JH, Kwon, JH, Kim, JW, Lee, M-S & Ham, B-J 2009, 'The neural substrates of affective face recognition in patients with Hwa-Byung and healthy individuals in Korea', World Journal of Biological Psychiatry, vol. 10, no. 4 PART 2, pp. 552-559. https://doi.org/10.1080/15622970802087130
Lee, Byeong Taek ; Paik, Jong Woo ; Kang, Rhee Hun ; Chung, Sun Yong ; Kwon, Ho In ; Khang, Hyun Soo ; Lyoo, In Kyoon ; Chae, Jeong Ho ; Kwon, Jung Hye ; Kim, Jong Woo ; Lee, Min-Soo ; Ham, Byung-Joo. / The neural substrates of affective face recognition in patients with Hwa-Byung and healthy individuals in Korea. In: World Journal of Biological Psychiatry. 2009 ; Vol. 10, No. 4 PART 2. pp. 552-559.
@article{e305ea80d16544f6a86dbd1a2090bd22,
title = "The neural substrates of affective face recognition in patients with Hwa-Byung and healthy individuals in Korea",
abstract = "Hwa-Byung (HB) is a Korean culture-bound psychiatric syndrome caused by the suppression of anger. HB patients have various psychological and somatic symptoms, such as chest discomfort, a sensation of heat, and the sensation of having an epigastric mass. In this study, we measured brain activity in HB patients and healthy individuals in response to affective facial stimuli. Using functional magnetic resonance imaging (fMRI), the current study measured neural responses to neutral, sad, and angry facial stimuli in 12 healthy individuals and 12 patients with HB. In response to all types of facial stimuli, HB patients showed increased activations in the lingual gyrus and fusiform gyrus compared with healthy persons, but they showed relatively lower activation in the thalamus. We also found that patients with HB showed lower activity in response to the neutral condition in the right ACC than healthy controls. The current study indicates that the suppression of affect results in aberrant function of the brain regions of the visual pathway, and functional impairment in the ACC may contribute to the pathophysiology of HB.",
keywords = "Anger, Functional magnetic resonance imaging (fMRI), Hwa-Byung, Sad, Visual pathway",
author = "Lee, {Byeong Taek} and Paik, {Jong Woo} and Kang, {Rhee Hun} and Chung, {Sun Yong} and Kwon, {Ho In} and Khang, {Hyun Soo} and Lyoo, {In Kyoon} and Chae, {Jeong Ho} and Kwon, {Jung Hye} and Kim, {Jong Woo} and Min-Soo Lee and Byung-Joo Ham",
year = "2009",
month = "12",
day = "1",
doi = "10.1080/15622970802087130",
language = "English",
volume = "10",
pages = "552--559",
journal = "World Journal of Biological Psychiatry",
issn = "1562-2975",
publisher = "Informa Healthcare",
number = "4 PART 2",

}

TY - JOUR

T1 - The neural substrates of affective face recognition in patients with Hwa-Byung and healthy individuals in Korea

AU - Lee, Byeong Taek

AU - Paik, Jong Woo

AU - Kang, Rhee Hun

AU - Chung, Sun Yong

AU - Kwon, Ho In

AU - Khang, Hyun Soo

AU - Lyoo, In Kyoon

AU - Chae, Jeong Ho

AU - Kwon, Jung Hye

AU - Kim, Jong Woo

AU - Lee, Min-Soo

AU - Ham, Byung-Joo

PY - 2009/12/1

Y1 - 2009/12/1

N2 - Hwa-Byung (HB) is a Korean culture-bound psychiatric syndrome caused by the suppression of anger. HB patients have various psychological and somatic symptoms, such as chest discomfort, a sensation of heat, and the sensation of having an epigastric mass. In this study, we measured brain activity in HB patients and healthy individuals in response to affective facial stimuli. Using functional magnetic resonance imaging (fMRI), the current study measured neural responses to neutral, sad, and angry facial stimuli in 12 healthy individuals and 12 patients with HB. In response to all types of facial stimuli, HB patients showed increased activations in the lingual gyrus and fusiform gyrus compared with healthy persons, but they showed relatively lower activation in the thalamus. We also found that patients with HB showed lower activity in response to the neutral condition in the right ACC than healthy controls. The current study indicates that the suppression of affect results in aberrant function of the brain regions of the visual pathway, and functional impairment in the ACC may contribute to the pathophysiology of HB.

AB - Hwa-Byung (HB) is a Korean culture-bound psychiatric syndrome caused by the suppression of anger. HB patients have various psychological and somatic symptoms, such as chest discomfort, a sensation of heat, and the sensation of having an epigastric mass. In this study, we measured brain activity in HB patients and healthy individuals in response to affective facial stimuli. Using functional magnetic resonance imaging (fMRI), the current study measured neural responses to neutral, sad, and angry facial stimuli in 12 healthy individuals and 12 patients with HB. In response to all types of facial stimuli, HB patients showed increased activations in the lingual gyrus and fusiform gyrus compared with healthy persons, but they showed relatively lower activation in the thalamus. We also found that patients with HB showed lower activity in response to the neutral condition in the right ACC than healthy controls. The current study indicates that the suppression of affect results in aberrant function of the brain regions of the visual pathway, and functional impairment in the ACC may contribute to the pathophysiology of HB.

KW - Anger

KW - Functional magnetic resonance imaging (fMRI)

KW - Hwa-Byung

KW - Sad

KW - Visual pathway

UR - http://www.scopus.com/inward/record.url?scp=77449091246&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77449091246&partnerID=8YFLogxK

U2 - 10.1080/15622970802087130

DO - 10.1080/15622970802087130

M3 - Article

VL - 10

SP - 552

EP - 559

JO - World Journal of Biological Psychiatry

JF - World Journal of Biological Psychiatry

SN - 1562-2975

IS - 4 PART 2

ER -