The prevalence of atopy and asthma among university freshmen in Seoul, Korea: Association with obesity

Young Yoo, Hong Ki Ko, Jae Joon Han, Yoon Lee, Kang Jin Seo, Ji Tae Choung, Young Chang Tockgo, Jae Gol Choe

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

The aims of this study were to investigate the prevalence of atopy, asthma, and obesity in university freshmen and to determine whether leptin is associated with bronchodilator reversibility in obesity. A total of 537 university freshmen completed International Study of Asthma and Allergies in Children (ISAAC) questionnaire and underwent skin prick testing and bronchodilator reversibility test. The prevalences of asthma, wheeze, and atopy were 10 (1.9%), 84 (15.6%), and 198 (36.9%), respectively. The mean (± SD) bronchodilator response (5.1 ± 4.4%) was higher in the overweight/obese men than in the normal male subjects (3.7 ± 3.2%, p < 0.05). The mean leptin level in the overweight/obese men was 5.55 ± 3.48 ng/mL, which was significantly higher than that (2.78 ± 1.65 ng/mL) of the normal male subjects. The prevalence of asthma among university freshmen is seriously under-diagnosed and leptin may play a role in bronchodilator reversibility in overweight/obese young men.

Original languageEnglish
Pages (from-to)45-49
Number of pages5
JournalJournal of Asthma
Volume44
Issue number1
DOIs
Publication statusPublished - 2007 Jan

Keywords

  • Asthma
  • Bronchodilator reversibility
  • Leptin
  • Obesity
  • University freshmen

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Immunology and Allergy
  • Pulmonary and Respiratory Medicine

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