The preventive effects of lifestyle intervention on the occurrence of diabetes mellitus and acute myocardial infarction in metabolic syndrome

D. Kim, Seok-Jun Yoon, Do-Sun Lim, Y. H. Gong, S. Ko, Y. H. Lee, H. S. Lee, M. S. Park, K. H. Kim, Y. A. Kim

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Objectives Metabolic syndrome (MS), as a precursor of diabetes mellitus (DM) and cardiovascular disease, is increasing steadily worldwide. We examined the preventive effects of lifestyle intervention on the occurrence of DM and acute myocardial infarction (AMI) in MS. Study design Observational study on disease occurrence after lifestyle intervention. Methods The lifestyle intervention was administered to subjects with MS participating in a metropolitan lifestyle intervention program for 1 year. The same numbers of non-participating age- and sex-matched subjects with MS were randomly extracted from national health examination data. After intervention or examination, new occurrences of hypertension, DM, and AMI were identified through the national health insurance claims data during 1 year. For DM and AMI, multivariate logistic regression analysis for the factors affecting each disease was performed. Results In the intervention group and the control group (14,918 in each group), the occurrence of hypertension was 555 (6.07%) and 751 (8.33%), the occurrence of DM was 324 (2.55%) and 488 (3.89%), the occurrence of dyslipidemia was 321 (2.59%) and 373 (2.72%), and the occurrence of AMI was 13 (0.09%) and 26 (0.17%), respectively. In multivariate logistic regression analysis, adjusted odds ratios for intervention were 0.752 (95% confidence interval [CI]: 0.644–0.879) and 0.499 (95% CI: 0.251–0.992) for DM and AMI, respectively, indicating that lifestyle intervention has a preventive effect. Conclusions Lifestyle intervention in MS has preventive effects on the occurrence of DM and AMI, and long-term follow-up is needed to evaluate these preventive effects in more detail.

Original languageEnglish
Pages (from-to)178-182
Number of pages5
JournalPublic Health
Volume139
DOIs
Publication statusPublished - 2016 Oct 1

Fingerprint

Life Style
Diabetes Mellitus
Myocardial Infarction
Logistic Models
Regression Analysis
Confidence Intervals
Hypertension
National Health Programs
Dyslipidemias
Observational Studies
Cardiovascular Diseases
Odds Ratio
Control Groups
Health

Keywords

  • Acute myocardial infarction
  • Diabetes mellitus
  • Lifestyle intervention
  • Metabolic syndrome

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health

Cite this

The preventive effects of lifestyle intervention on the occurrence of diabetes mellitus and acute myocardial infarction in metabolic syndrome. / Kim, D.; Yoon, Seok-Jun; Lim, Do-Sun; Gong, Y. H.; Ko, S.; Lee, Y. H.; Lee, H. S.; Park, M. S.; Kim, K. H.; Kim, Y. A.

In: Public Health, Vol. 139, 01.10.2016, p. 178-182.

Research output: Contribution to journalArticle

Kim, D. ; Yoon, Seok-Jun ; Lim, Do-Sun ; Gong, Y. H. ; Ko, S. ; Lee, Y. H. ; Lee, H. S. ; Park, M. S. ; Kim, K. H. ; Kim, Y. A. / The preventive effects of lifestyle intervention on the occurrence of diabetes mellitus and acute myocardial infarction in metabolic syndrome. In: Public Health. 2016 ; Vol. 139. pp. 178-182.
@article{ed3d583c8bb54b188a2cc683860f2176,
title = "The preventive effects of lifestyle intervention on the occurrence of diabetes mellitus and acute myocardial infarction in metabolic syndrome",
abstract = "Objectives Metabolic syndrome (MS), as a precursor of diabetes mellitus (DM) and cardiovascular disease, is increasing steadily worldwide. We examined the preventive effects of lifestyle intervention on the occurrence of DM and acute myocardial infarction (AMI) in MS. Study design Observational study on disease occurrence after lifestyle intervention. Methods The lifestyle intervention was administered to subjects with MS participating in a metropolitan lifestyle intervention program for 1 year. The same numbers of non-participating age- and sex-matched subjects with MS were randomly extracted from national health examination data. After intervention or examination, new occurrences of hypertension, DM, and AMI were identified through the national health insurance claims data during 1 year. For DM and AMI, multivariate logistic regression analysis for the factors affecting each disease was performed. Results In the intervention group and the control group (14,918 in each group), the occurrence of hypertension was 555 (6.07{\%}) and 751 (8.33{\%}), the occurrence of DM was 324 (2.55{\%}) and 488 (3.89{\%}), the occurrence of dyslipidemia was 321 (2.59{\%}) and 373 (2.72{\%}), and the occurrence of AMI was 13 (0.09{\%}) and 26 (0.17{\%}), respectively. In multivariate logistic regression analysis, adjusted odds ratios for intervention were 0.752 (95{\%} confidence interval [CI]: 0.644–0.879) and 0.499 (95{\%} CI: 0.251–0.992) for DM and AMI, respectively, indicating that lifestyle intervention has a preventive effect. Conclusions Lifestyle intervention in MS has preventive effects on the occurrence of DM and AMI, and long-term follow-up is needed to evaluate these preventive effects in more detail.",
keywords = "Acute myocardial infarction, Diabetes mellitus, Lifestyle intervention, Metabolic syndrome",
author = "D. Kim and Seok-Jun Yoon and Do-Sun Lim and Gong, {Y. H.} and S. Ko and Lee, {Y. H.} and Lee, {H. S.} and Park, {M. S.} and Kim, {K. H.} and Kim, {Y. A.}",
year = "2016",
month = "10",
day = "1",
doi = "10.1016/j.puhe.2016.06.012",
language = "English",
volume = "139",
pages = "178--182",
journal = "Public Health",
issn = "0033-3506",
publisher = "Elsevier",

}

TY - JOUR

T1 - The preventive effects of lifestyle intervention on the occurrence of diabetes mellitus and acute myocardial infarction in metabolic syndrome

AU - Kim, D.

AU - Yoon, Seok-Jun

AU - Lim, Do-Sun

AU - Gong, Y. H.

AU - Ko, S.

AU - Lee, Y. H.

AU - Lee, H. S.

AU - Park, M. S.

AU - Kim, K. H.

AU - Kim, Y. A.

PY - 2016/10/1

Y1 - 2016/10/1

N2 - Objectives Metabolic syndrome (MS), as a precursor of diabetes mellitus (DM) and cardiovascular disease, is increasing steadily worldwide. We examined the preventive effects of lifestyle intervention on the occurrence of DM and acute myocardial infarction (AMI) in MS. Study design Observational study on disease occurrence after lifestyle intervention. Methods The lifestyle intervention was administered to subjects with MS participating in a metropolitan lifestyle intervention program for 1 year. The same numbers of non-participating age- and sex-matched subjects with MS were randomly extracted from national health examination data. After intervention or examination, new occurrences of hypertension, DM, and AMI were identified through the national health insurance claims data during 1 year. For DM and AMI, multivariate logistic regression analysis for the factors affecting each disease was performed. Results In the intervention group and the control group (14,918 in each group), the occurrence of hypertension was 555 (6.07%) and 751 (8.33%), the occurrence of DM was 324 (2.55%) and 488 (3.89%), the occurrence of dyslipidemia was 321 (2.59%) and 373 (2.72%), and the occurrence of AMI was 13 (0.09%) and 26 (0.17%), respectively. In multivariate logistic regression analysis, adjusted odds ratios for intervention were 0.752 (95% confidence interval [CI]: 0.644–0.879) and 0.499 (95% CI: 0.251–0.992) for DM and AMI, respectively, indicating that lifestyle intervention has a preventive effect. Conclusions Lifestyle intervention in MS has preventive effects on the occurrence of DM and AMI, and long-term follow-up is needed to evaluate these preventive effects in more detail.

AB - Objectives Metabolic syndrome (MS), as a precursor of diabetes mellitus (DM) and cardiovascular disease, is increasing steadily worldwide. We examined the preventive effects of lifestyle intervention on the occurrence of DM and acute myocardial infarction (AMI) in MS. Study design Observational study on disease occurrence after lifestyle intervention. Methods The lifestyle intervention was administered to subjects with MS participating in a metropolitan lifestyle intervention program for 1 year. The same numbers of non-participating age- and sex-matched subjects with MS were randomly extracted from national health examination data. After intervention or examination, new occurrences of hypertension, DM, and AMI were identified through the national health insurance claims data during 1 year. For DM and AMI, multivariate logistic regression analysis for the factors affecting each disease was performed. Results In the intervention group and the control group (14,918 in each group), the occurrence of hypertension was 555 (6.07%) and 751 (8.33%), the occurrence of DM was 324 (2.55%) and 488 (3.89%), the occurrence of dyslipidemia was 321 (2.59%) and 373 (2.72%), and the occurrence of AMI was 13 (0.09%) and 26 (0.17%), respectively. In multivariate logistic regression analysis, adjusted odds ratios for intervention were 0.752 (95% confidence interval [CI]: 0.644–0.879) and 0.499 (95% CI: 0.251–0.992) for DM and AMI, respectively, indicating that lifestyle intervention has a preventive effect. Conclusions Lifestyle intervention in MS has preventive effects on the occurrence of DM and AMI, and long-term follow-up is needed to evaluate these preventive effects in more detail.

KW - Acute myocardial infarction

KW - Diabetes mellitus

KW - Lifestyle intervention

KW - Metabolic syndrome

UR - http://www.scopus.com/inward/record.url?scp=84991071122&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84991071122&partnerID=8YFLogxK

U2 - 10.1016/j.puhe.2016.06.012

DO - 10.1016/j.puhe.2016.06.012

M3 - Article

VL - 139

SP - 178

EP - 182

JO - Public Health

JF - Public Health

SN - 0033-3506

ER -