Abstract
ABSTRACT:: Meibomian gland dysfunction (MGD) is a leading cause of dry eye disease (DED). Meibomian gland dysfunction is divided into two major categories based on meibomian gland secretion: low delivery and high delivery. The low-delivery states are further classified as either hyposecretory or obstructive subtype, and the high-delivery state is termed “hypersecretory MGD.” Two parameters are commonly used to evaluate meibomian gland function: lipid layer thickness and meibum quality and expressibility. To evaluate the morphology of meibomian glands, meibography is used to detect meibomian gland dropout. Functional and morphological changes of meibomian glands are often thought to be well correlated; in reality, many cases do not because some patients have characteristics of both hypersecretory and obstructive subtypes. We suggest that the MGD classification system should be modified to include a mixed subtype to explain such patients.
| Original language | English |
|---|---|
| Journal | Eye and Contact Lens |
| DOIs | |
| Publication status | Accepted/In press - 2016 Oct 13 |
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ASJC Scopus subject areas
- Ophthalmology
Cite this
The Relationship Between Morphology and Function of the Meibomian Glands. / Kim, Hyo Myung; Eom, Youngsub; Song, Jong-Suk.
In: Eye and Contact Lens, 13.10.2016.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - The Relationship Between Morphology and Function of the Meibomian Glands
AU - Kim, Hyo Myung
AU - Eom, Youngsub
AU - Song, Jong-Suk
PY - 2016/10/13
Y1 - 2016/10/13
N2 - ABSTRACT:: Meibomian gland dysfunction (MGD) is a leading cause of dry eye disease (DED). Meibomian gland dysfunction is divided into two major categories based on meibomian gland secretion: low delivery and high delivery. The low-delivery states are further classified as either hyposecretory or obstructive subtype, and the high-delivery state is termed “hypersecretory MGD.” Two parameters are commonly used to evaluate meibomian gland function: lipid layer thickness and meibum quality and expressibility. To evaluate the morphology of meibomian glands, meibography is used to detect meibomian gland dropout. Functional and morphological changes of meibomian glands are often thought to be well correlated; in reality, many cases do not because some patients have characteristics of both hypersecretory and obstructive subtypes. We suggest that the MGD classification system should be modified to include a mixed subtype to explain such patients.
AB - ABSTRACT:: Meibomian gland dysfunction (MGD) is a leading cause of dry eye disease (DED). Meibomian gland dysfunction is divided into two major categories based on meibomian gland secretion: low delivery and high delivery. The low-delivery states are further classified as either hyposecretory or obstructive subtype, and the high-delivery state is termed “hypersecretory MGD.” Two parameters are commonly used to evaluate meibomian gland function: lipid layer thickness and meibum quality and expressibility. To evaluate the morphology of meibomian glands, meibography is used to detect meibomian gland dropout. Functional and morphological changes of meibomian glands are often thought to be well correlated; in reality, many cases do not because some patients have characteristics of both hypersecretory and obstructive subtypes. We suggest that the MGD classification system should be modified to include a mixed subtype to explain such patients.
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UR - http://www.scopus.com/inward/citedby.url?scp=84991717332&partnerID=8YFLogxK
U2 - 10.1097/ICL.0000000000000336
DO - 10.1097/ICL.0000000000000336
M3 - Article
C2 - 27755288
AN - SCOPUS:84991717332
JO - Eye and Contact Lens
JF - Eye and Contact Lens
SN - 1542-2321
ER -