Abstract
Background: Arterial stiffness has been suggested as a valuable predictor of coronary artery stenosis (CAS). However, little data are available on aortic stiffness and CAS in patients who have previously undergone percutaneous coronary artery intervention (PCI). The aim of this study was to investigate the association of arterial stiffness to CAS in patients with a history of PCI and those without a history of PCI. Methods: We retrospectively studied 1093 consecutive patients who had undergone coronary angiography (CAG). Arterial stiffness was determined by brachial-ankle pulse wave velocity (baPWV) measured prior to CAG. Results: In patients without a history of PCI, baPWV significantly increased in patients with CAS compared to that in patients without CAS (p<0.001). However, among patients with a history of PCI, there was no significant difference in baPWV. Multivariate logistic regression analysis demonstrated that baPWV was an independent risk predictor for CAS in patients without a history of PCI, but not in those with a history of PCI (OR 1.106, 95% CI 1.039-1.177, p=0.002). In CAS patients without a history of PCI, increased baPWV was significantly associated with multiple cardiovascular risk factors, multivessel involvement, and anatomical severity. Conclusions: Prediction of CAS by baPWV is significantly attenuated in patients with a history of PCI.
| Original language | English |
|---|---|
| Article number | 45 |
| Journal | BMC Cardiovascular Disorders |
| Volume | 17 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 2017 Jan 31 |
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Keywords
- Aortic stiffness
- Coronary artery stenosis
- Percutaneous coronary artery intervention
- Pulse wave velocity
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
Cite this
The Relationship between Pulse Wave Velocity and Coronary Artery Stenosis and Percutaneous Coronary Intervention : A retrospective observational study. / Joo, Hyung Joon; Cho, Sang A.; Cho, Jae Young; Park, Jae Hyoung; Hong, Soon Jun; Yu, Cheol Woong; Lim, Do-Sun.
In: BMC Cardiovascular Disorders, Vol. 17, No. 1, 45, 31.01.2017.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - The Relationship between Pulse Wave Velocity and Coronary Artery Stenosis and Percutaneous Coronary Intervention
T2 - A retrospective observational study
AU - Joo, Hyung Joon
AU - Cho, Sang A.
AU - Cho, Jae Young
AU - Park, Jae Hyoung
AU - Hong, Soon Jun
AU - Yu, Cheol Woong
AU - Lim, Do-Sun
PY - 2017/1/31
Y1 - 2017/1/31
N2 - Background: Arterial stiffness has been suggested as a valuable predictor of coronary artery stenosis (CAS). However, little data are available on aortic stiffness and CAS in patients who have previously undergone percutaneous coronary artery intervention (PCI). The aim of this study was to investigate the association of arterial stiffness to CAS in patients with a history of PCI and those without a history of PCI. Methods: We retrospectively studied 1093 consecutive patients who had undergone coronary angiography (CAG). Arterial stiffness was determined by brachial-ankle pulse wave velocity (baPWV) measured prior to CAG. Results: In patients without a history of PCI, baPWV significantly increased in patients with CAS compared to that in patients without CAS (p<0.001). However, among patients with a history of PCI, there was no significant difference in baPWV. Multivariate logistic regression analysis demonstrated that baPWV was an independent risk predictor for CAS in patients without a history of PCI, but not in those with a history of PCI (OR 1.106, 95% CI 1.039-1.177, p=0.002). In CAS patients without a history of PCI, increased baPWV was significantly associated with multiple cardiovascular risk factors, multivessel involvement, and anatomical severity. Conclusions: Prediction of CAS by baPWV is significantly attenuated in patients with a history of PCI.
AB - Background: Arterial stiffness has been suggested as a valuable predictor of coronary artery stenosis (CAS). However, little data are available on aortic stiffness and CAS in patients who have previously undergone percutaneous coronary artery intervention (PCI). The aim of this study was to investigate the association of arterial stiffness to CAS in patients with a history of PCI and those without a history of PCI. Methods: We retrospectively studied 1093 consecutive patients who had undergone coronary angiography (CAG). Arterial stiffness was determined by brachial-ankle pulse wave velocity (baPWV) measured prior to CAG. Results: In patients without a history of PCI, baPWV significantly increased in patients with CAS compared to that in patients without CAS (p<0.001). However, among patients with a history of PCI, there was no significant difference in baPWV. Multivariate logistic regression analysis demonstrated that baPWV was an independent risk predictor for CAS in patients without a history of PCI, but not in those with a history of PCI (OR 1.106, 95% CI 1.039-1.177, p=0.002). In CAS patients without a history of PCI, increased baPWV was significantly associated with multiple cardiovascular risk factors, multivessel involvement, and anatomical severity. Conclusions: Prediction of CAS by baPWV is significantly attenuated in patients with a history of PCI.
KW - Aortic stiffness
KW - Coronary artery stenosis
KW - Percutaneous coronary artery intervention
KW - Pulse wave velocity
UR - http://www.scopus.com/inward/record.url?scp=85011072575&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85011072575&partnerID=8YFLogxK
U2 - 10.1186/s12872-017-0476-7
DO - 10.1186/s12872-017-0476-7
M3 - Article
C2 - 28137285
AN - SCOPUS:85011072575
VL - 17
JO - BMC Cardiovascular Disorders
JF - BMC Cardiovascular Disorders
SN - 1471-2261
IS - 1
M1 - 45
ER -