The Relationship between Pulse Wave Velocity and Coronary Artery Stenosis and Percutaneous Coronary Intervention: A retrospective observational study

Hyung Joon Joo, Sang A. Cho, Jae Young Cho, Jae Hyoung Park, Soon Jun Hong, Cheol Woong Yu, Do-Sun Lim

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Background: Arterial stiffness has been suggested as a valuable predictor of coronary artery stenosis (CAS). However, little data are available on aortic stiffness and CAS in patients who have previously undergone percutaneous coronary artery intervention (PCI). The aim of this study was to investigate the association of arterial stiffness to CAS in patients with a history of PCI and those without a history of PCI. Methods: We retrospectively studied 1093 consecutive patients who had undergone coronary angiography (CAG). Arterial stiffness was determined by brachial-ankle pulse wave velocity (baPWV) measured prior to CAG. Results: In patients without a history of PCI, baPWV significantly increased in patients with CAS compared to that in patients without CAS (p<0.001). However, among patients with a history of PCI, there was no significant difference in baPWV. Multivariate logistic regression analysis demonstrated that baPWV was an independent risk predictor for CAS in patients without a history of PCI, but not in those with a history of PCI (OR 1.106, 95% CI 1.039-1.177, p=0.002). In CAS patients without a history of PCI, increased baPWV was significantly associated with multiple cardiovascular risk factors, multivessel involvement, and anatomical severity. Conclusions: Prediction of CAS by baPWV is significantly attenuated in patients with a history of PCI.

Original languageEnglish
Article number45
JournalBMC Cardiovascular Disorders
Volume17
Issue number1
DOIs
Publication statusPublished - 2017 Jan 31

Fingerprint

Pulse Wave Analysis
Coronary Stenosis
Percutaneous Coronary Intervention
Observational Studies
Retrospective Studies
Coronary Vessels
Ankle
Vascular Stiffness
Arm
Coronary Angiography
Logistic Models
Regression Analysis

Keywords

  • Aortic stiffness
  • Coronary artery stenosis
  • Percutaneous coronary artery intervention
  • Pulse wave velocity

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

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title = "The Relationship between Pulse Wave Velocity and Coronary Artery Stenosis and Percutaneous Coronary Intervention: A retrospective observational study",
abstract = "Background: Arterial stiffness has been suggested as a valuable predictor of coronary artery stenosis (CAS). However, little data are available on aortic stiffness and CAS in patients who have previously undergone percutaneous coronary artery intervention (PCI). The aim of this study was to investigate the association of arterial stiffness to CAS in patients with a history of PCI and those without a history of PCI. Methods: We retrospectively studied 1093 consecutive patients who had undergone coronary angiography (CAG). Arterial stiffness was determined by brachial-ankle pulse wave velocity (baPWV) measured prior to CAG. Results: In patients without a history of PCI, baPWV significantly increased in patients with CAS compared to that in patients without CAS (p<0.001). However, among patients with a history of PCI, there was no significant difference in baPWV. Multivariate logistic regression analysis demonstrated that baPWV was an independent risk predictor for CAS in patients without a history of PCI, but not in those with a history of PCI (OR 1.106, 95{\%} CI 1.039-1.177, p=0.002). In CAS patients without a history of PCI, increased baPWV was significantly associated with multiple cardiovascular risk factors, multivessel involvement, and anatomical severity. Conclusions: Prediction of CAS by baPWV is significantly attenuated in patients with a history of PCI.",
keywords = "Aortic stiffness, Coronary artery stenosis, Percutaneous coronary artery intervention, Pulse wave velocity",
author = "Joo, {Hyung Joon} and Cho, {Sang A.} and Cho, {Jae Young} and Park, {Jae Hyoung} and Hong, {Soon Jun} and Yu, {Cheol Woong} and Do-Sun Lim",
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T1 - The Relationship between Pulse Wave Velocity and Coronary Artery Stenosis and Percutaneous Coronary Intervention

T2 - A retrospective observational study

AU - Joo, Hyung Joon

AU - Cho, Sang A.

AU - Cho, Jae Young

AU - Park, Jae Hyoung

AU - Hong, Soon Jun

AU - Yu, Cheol Woong

AU - Lim, Do-Sun

PY - 2017/1/31

Y1 - 2017/1/31

N2 - Background: Arterial stiffness has been suggested as a valuable predictor of coronary artery stenosis (CAS). However, little data are available on aortic stiffness and CAS in patients who have previously undergone percutaneous coronary artery intervention (PCI). The aim of this study was to investigate the association of arterial stiffness to CAS in patients with a history of PCI and those without a history of PCI. Methods: We retrospectively studied 1093 consecutive patients who had undergone coronary angiography (CAG). Arterial stiffness was determined by brachial-ankle pulse wave velocity (baPWV) measured prior to CAG. Results: In patients without a history of PCI, baPWV significantly increased in patients with CAS compared to that in patients without CAS (p<0.001). However, among patients with a history of PCI, there was no significant difference in baPWV. Multivariate logistic regression analysis demonstrated that baPWV was an independent risk predictor for CAS in patients without a history of PCI, but not in those with a history of PCI (OR 1.106, 95% CI 1.039-1.177, p=0.002). In CAS patients without a history of PCI, increased baPWV was significantly associated with multiple cardiovascular risk factors, multivessel involvement, and anatomical severity. Conclusions: Prediction of CAS by baPWV is significantly attenuated in patients with a history of PCI.

AB - Background: Arterial stiffness has been suggested as a valuable predictor of coronary artery stenosis (CAS). However, little data are available on aortic stiffness and CAS in patients who have previously undergone percutaneous coronary artery intervention (PCI). The aim of this study was to investigate the association of arterial stiffness to CAS in patients with a history of PCI and those without a history of PCI. Methods: We retrospectively studied 1093 consecutive patients who had undergone coronary angiography (CAG). Arterial stiffness was determined by brachial-ankle pulse wave velocity (baPWV) measured prior to CAG. Results: In patients without a history of PCI, baPWV significantly increased in patients with CAS compared to that in patients without CAS (p<0.001). However, among patients with a history of PCI, there was no significant difference in baPWV. Multivariate logistic regression analysis demonstrated that baPWV was an independent risk predictor for CAS in patients without a history of PCI, but not in those with a history of PCI (OR 1.106, 95% CI 1.039-1.177, p=0.002). In CAS patients without a history of PCI, increased baPWV was significantly associated with multiple cardiovascular risk factors, multivessel involvement, and anatomical severity. Conclusions: Prediction of CAS by baPWV is significantly attenuated in patients with a history of PCI.

KW - Aortic stiffness

KW - Coronary artery stenosis

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KW - Pulse wave velocity

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