The role of dynamic changes in blood perfusion and optical properties in thermal coagulation of the prostate

Beop Min Kim, Steven L. Jacques, Sohi Rastegar, Sharon Thomsen, Massoud Motamedi

Research output: Contribution to journalConference article

16 Citations (Scopus)

Abstract

The dynamic evolution of the coagulation front in laser irradiated prostate tissue is simulated using a nonlinear finite element method (NFEM) which takes into account the temperature and thermal damage dependence of blood perfusion rate and optical properties. Using this nonlinear model, it wasfound that the hyperemic ringformed at the periphery of the coagulationfront reduces heatpenetration significantly and the increased scattering near the tissue surface reduces the light energy deposition in the deep region. Thefinal damage depth would be overestimated by about 50% ifthe effect oftemperature and damage dependence of blood perfusion and opticalproperties modeling is disregarded.

Original languageEnglish
Pages (from-to)443-450
Number of pages8
JournalProceedings of SPIE - The International Society for Optical Engineering
Volume2391
DOIs
Publication statusPublished - 1995 May 22
Externally publishedYes
EventLaser-Tissue Interaction VI 1995 - San Jose, United States
Duration: 1995 Feb 11995 Feb 8

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering

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