The safety of reused endotracheal tubes sterilized according to Centers for Disease Control and Prevention guidelines

Seung-Zhoo Yoon, Yun Seok Jeon, Yong C. Kim, Young J. Lim, Jin W. Ha, Jae H. Bahk, Sang H. Do, Kook H. Lee, Chong S. Kim

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Study Objective: To investigate safety issues associated with the reuse of sterilized endotracheal tubes (ETTs). Design: Prospective, randomized study. Setting: Laboratory in vivo testing. Intervention: Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa were inoculated onto ETT cuffs. Following inoculation, ETTs were sterilized with either ethylene oxide or glutaraldehyde. Cuffs were then swabbed and cultured for 24 hours. To examine changes in the physical integrities of sterilized ETT cuffs, ETTs were sterilized with ethylene oxide gas once, twice, or three times (the E1, E2, and E3 groups, respectively). Alternatively, ETTs were soaked in glutaraldehyde for 150, 300, 450, or 600 minutes (the G1, G2, G3, and G4 groups, respectively). Measurements: Endotracheal tube cuffs were considered nonsterile if a visible colony of test organisms was cultured, and sterile if no colony was cultured. Changes in the physical integrity of sterilized ETT cuffs were determined by measuring changes in intracuff pressure or tensile strength. Main Results: No growth of bacteria was observed in sterilized tubes. Endotracheal tube cuffs of the E1 and E2 groups showed almost the same physical integrity as those of the control group, whereas E3 group cuffs were softer than those of the untreated controls. Endotracheal tube cuffs of the G1 and G2 groups were harder than untreated controls; than of those of the G3 and G4 groups were similar to the controls. Conclusions: Endotracheal tubes can be reused sterilized safely. The physical integrity of ETT cuffs may be compromised by glutaraldehyde or ethylene oxide sterilization treatments.

Original languageEnglish
Pages (from-to)360-364
Number of pages5
JournalJournal of Clinical Anesthesia
Volume19
Issue number5
DOIs
Publication statusPublished - 2007 Aug 1
Externally publishedYes

Fingerprint

Ethylene Oxide
Glutaral
Centers for Disease Control and Prevention (U.S.)
Guidelines
Safety
Tensile Strength
Pseudomonas aeruginosa
Staphylococcus aureus
Gases
Prospective Studies
Escherichia coli
Bacteria
Pressure
Control Groups
Growth

Keywords

  • Ethylene oxide
  • Glutaraldehyde
  • Intubation, intratracheal
  • Reusable equipment
  • Sterilization

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

Cite this

The safety of reused endotracheal tubes sterilized according to Centers for Disease Control and Prevention guidelines. / Yoon, Seung-Zhoo; Jeon, Yun Seok; Kim, Yong C.; Lim, Young J.; Ha, Jin W.; Bahk, Jae H.; Do, Sang H.; Lee, Kook H.; Kim, Chong S.

In: Journal of Clinical Anesthesia, Vol. 19, No. 5, 01.08.2007, p. 360-364.

Research output: Contribution to journalArticle

Yoon, Seung-Zhoo ; Jeon, Yun Seok ; Kim, Yong C. ; Lim, Young J. ; Ha, Jin W. ; Bahk, Jae H. ; Do, Sang H. ; Lee, Kook H. ; Kim, Chong S. / The safety of reused endotracheal tubes sterilized according to Centers for Disease Control and Prevention guidelines. In: Journal of Clinical Anesthesia. 2007 ; Vol. 19, No. 5. pp. 360-364.
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abstract = "Study Objective: To investigate safety issues associated with the reuse of sterilized endotracheal tubes (ETTs). Design: Prospective, randomized study. Setting: Laboratory in vivo testing. Intervention: Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa were inoculated onto ETT cuffs. Following inoculation, ETTs were sterilized with either ethylene oxide or glutaraldehyde. Cuffs were then swabbed and cultured for 24 hours. To examine changes in the physical integrities of sterilized ETT cuffs, ETTs were sterilized with ethylene oxide gas once, twice, or three times (the E1, E2, and E3 groups, respectively). Alternatively, ETTs were soaked in glutaraldehyde for 150, 300, 450, or 600 minutes (the G1, G2, G3, and G4 groups, respectively). Measurements: Endotracheal tube cuffs were considered nonsterile if a visible colony of test organisms was cultured, and sterile if no colony was cultured. Changes in the physical integrity of sterilized ETT cuffs were determined by measuring changes in intracuff pressure or tensile strength. Main Results: No growth of bacteria was observed in sterilized tubes. Endotracheal tube cuffs of the E1 and E2 groups showed almost the same physical integrity as those of the control group, whereas E3 group cuffs were softer than those of the untreated controls. Endotracheal tube cuffs of the G1 and G2 groups were harder than untreated controls; than of those of the G3 and G4 groups were similar to the controls. Conclusions: Endotracheal tubes can be reused sterilized safely. The physical integrity of ETT cuffs may be compromised by glutaraldehyde or ethylene oxide sterilization treatments.",
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AU - Yoon, Seung-Zhoo

AU - Jeon, Yun Seok

AU - Kim, Yong C.

AU - Lim, Young J.

AU - Ha, Jin W.

AU - Bahk, Jae H.

AU - Do, Sang H.

AU - Lee, Kook H.

AU - Kim, Chong S.

PY - 2007/8/1

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N2 - Study Objective: To investigate safety issues associated with the reuse of sterilized endotracheal tubes (ETTs). Design: Prospective, randomized study. Setting: Laboratory in vivo testing. Intervention: Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa were inoculated onto ETT cuffs. Following inoculation, ETTs were sterilized with either ethylene oxide or glutaraldehyde. Cuffs were then swabbed and cultured for 24 hours. To examine changes in the physical integrities of sterilized ETT cuffs, ETTs were sterilized with ethylene oxide gas once, twice, or three times (the E1, E2, and E3 groups, respectively). Alternatively, ETTs were soaked in glutaraldehyde for 150, 300, 450, or 600 minutes (the G1, G2, G3, and G4 groups, respectively). Measurements: Endotracheal tube cuffs were considered nonsterile if a visible colony of test organisms was cultured, and sterile if no colony was cultured. Changes in the physical integrity of sterilized ETT cuffs were determined by measuring changes in intracuff pressure or tensile strength. Main Results: No growth of bacteria was observed in sterilized tubes. Endotracheal tube cuffs of the E1 and E2 groups showed almost the same physical integrity as those of the control group, whereas E3 group cuffs were softer than those of the untreated controls. Endotracheal tube cuffs of the G1 and G2 groups were harder than untreated controls; than of those of the G3 and G4 groups were similar to the controls. Conclusions: Endotracheal tubes can be reused sterilized safely. The physical integrity of ETT cuffs may be compromised by glutaraldehyde or ethylene oxide sterilization treatments.

AB - Study Objective: To investigate safety issues associated with the reuse of sterilized endotracheal tubes (ETTs). Design: Prospective, randomized study. Setting: Laboratory in vivo testing. Intervention: Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa were inoculated onto ETT cuffs. Following inoculation, ETTs were sterilized with either ethylene oxide or glutaraldehyde. Cuffs were then swabbed and cultured for 24 hours. To examine changes in the physical integrities of sterilized ETT cuffs, ETTs were sterilized with ethylene oxide gas once, twice, or three times (the E1, E2, and E3 groups, respectively). Alternatively, ETTs were soaked in glutaraldehyde for 150, 300, 450, or 600 minutes (the G1, G2, G3, and G4 groups, respectively). Measurements: Endotracheal tube cuffs were considered nonsterile if a visible colony of test organisms was cultured, and sterile if no colony was cultured. Changes in the physical integrity of sterilized ETT cuffs were determined by measuring changes in intracuff pressure or tensile strength. Main Results: No growth of bacteria was observed in sterilized tubes. Endotracheal tube cuffs of the E1 and E2 groups showed almost the same physical integrity as those of the control group, whereas E3 group cuffs were softer than those of the untreated controls. Endotracheal tube cuffs of the G1 and G2 groups were harder than untreated controls; than of those of the G3 and G4 groups were similar to the controls. Conclusions: Endotracheal tubes can be reused sterilized safely. The physical integrity of ETT cuffs may be compromised by glutaraldehyde or ethylene oxide sterilization treatments.

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KW - Intubation, intratracheal

KW - Reusable equipment

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