The sensitivity of gas chromatography-headspace solid phase microextraction in relationship with relative volatility of volatile organic compounds

Ki Hyun Kim, Sudhir Kumar Pandey, Jong Ryeul Sohn

Research output: Contribution to journalArticle

Abstract

In order to explore the analytical performance of Headspace-Solid-phase Microextraction (HS-SPME), the sensitivity of gas chromatography (GC)-Mass Spectrometry (MS) determinations was examined in terms of calibration slopes, that is, response factor values of selected volatile organic compounds (VOC). The HS-SPME was applied to extract two kinds of gaseous VOC analytes, namely group I (methyl ethyl ketone, isobutyl alcohol, methyl isobutyl ketone, and butyl acetate, all having high water solubility) and group II (benzene, toluene, styrene, and xylene, all having moderate water solubility) from water solutions. The results, derived by both external and internal calibration, were then evaluated by considering headspace sample volume and solute volatility. In the case of solutes consisting of group I, sensitivity seems to increase with increasing HS size, although there are no such discernible patterns for group II solutes. The observed relative patterns in extraction efficiency may be accounted for by the differences in intermolecular forces present between the compounds of groups I and II and the possible effects of diffusion kinetics of the VOCs to the SPME fiber or competitive adsorption between different VOCs. As such, sensitivity of HS-SPME is tightly affected by the air-water partitioning properties of the target compounds and the response of SPME to such properties.

Original languageEnglish
Pages (from-to)2457-2465
Number of pages9
JournalAnalytical Letters
Volume44
Issue number15
DOIs
Publication statusPublished - 2011 Oct 1

Fingerprint

Volatile Organic Compounds
Solid Phase Microextraction
Volatilization
Volatile organic compounds
Gas chromatography
Gas Chromatography
Water
Ketones
Solubility
Calibration
Xylenes
Styrene
Toluene
Xylene
Benzene
Gas Chromatography-Mass Spectrometry
Adsorption
Mass spectrometry
Methanol
Air

Keywords

  • Environmental air samples
  • Gas chromatography with mass spectrometry
  • Odorants
  • Solid phase microextraction
  • Volatile organic compounds

ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry
  • Clinical Biochemistry
  • Biochemistry, medical
  • Electrochemistry
  • Spectroscopy

Cite this

The sensitivity of gas chromatography-headspace solid phase microextraction in relationship with relative volatility of volatile organic compounds. / Kim, Ki Hyun; Pandey, Sudhir Kumar; Sohn, Jong Ryeul.

In: Analytical Letters, Vol. 44, No. 15, 01.10.2011, p. 2457-2465.

Research output: Contribution to journalArticle

@article{1487feab39a5408081689bfd6256e385,
title = "The sensitivity of gas chromatography-headspace solid phase microextraction in relationship with relative volatility of volatile organic compounds",
abstract = "In order to explore the analytical performance of Headspace-Solid-phase Microextraction (HS-SPME), the sensitivity of gas chromatography (GC)-Mass Spectrometry (MS) determinations was examined in terms of calibration slopes, that is, response factor values of selected volatile organic compounds (VOC). The HS-SPME was applied to extract two kinds of gaseous VOC analytes, namely group I (methyl ethyl ketone, isobutyl alcohol, methyl isobutyl ketone, and butyl acetate, all having high water solubility) and group II (benzene, toluene, styrene, and xylene, all having moderate water solubility) from water solutions. The results, derived by both external and internal calibration, were then evaluated by considering headspace sample volume and solute volatility. In the case of solutes consisting of group I, sensitivity seems to increase with increasing HS size, although there are no such discernible patterns for group II solutes. The observed relative patterns in extraction efficiency may be accounted for by the differences in intermolecular forces present between the compounds of groups I and II and the possible effects of diffusion kinetics of the VOCs to the SPME fiber or competitive adsorption between different VOCs. As such, sensitivity of HS-SPME is tightly affected by the air-water partitioning properties of the target compounds and the response of SPME to such properties.",
keywords = "Environmental air samples, Gas chromatography with mass spectrometry, Odorants, Solid phase microextraction, Volatile organic compounds",
author = "Kim, {Ki Hyun} and Pandey, {Sudhir Kumar} and Sohn, {Jong Ryeul}",
year = "2011",
month = "10",
day = "1",
doi = "10.1080/00032719.2011.551854",
language = "English",
volume = "44",
pages = "2457--2465",
journal = "Analytical Letters",
issn = "0003-2719",
publisher = "Taylor and Francis Ltd.",
number = "15",

}

TY - JOUR

T1 - The sensitivity of gas chromatography-headspace solid phase microextraction in relationship with relative volatility of volatile organic compounds

AU - Kim, Ki Hyun

AU - Pandey, Sudhir Kumar

AU - Sohn, Jong Ryeul

PY - 2011/10/1

Y1 - 2011/10/1

N2 - In order to explore the analytical performance of Headspace-Solid-phase Microextraction (HS-SPME), the sensitivity of gas chromatography (GC)-Mass Spectrometry (MS) determinations was examined in terms of calibration slopes, that is, response factor values of selected volatile organic compounds (VOC). The HS-SPME was applied to extract two kinds of gaseous VOC analytes, namely group I (methyl ethyl ketone, isobutyl alcohol, methyl isobutyl ketone, and butyl acetate, all having high water solubility) and group II (benzene, toluene, styrene, and xylene, all having moderate water solubility) from water solutions. The results, derived by both external and internal calibration, were then evaluated by considering headspace sample volume and solute volatility. In the case of solutes consisting of group I, sensitivity seems to increase with increasing HS size, although there are no such discernible patterns for group II solutes. The observed relative patterns in extraction efficiency may be accounted for by the differences in intermolecular forces present between the compounds of groups I and II and the possible effects of diffusion kinetics of the VOCs to the SPME fiber or competitive adsorption between different VOCs. As such, sensitivity of HS-SPME is tightly affected by the air-water partitioning properties of the target compounds and the response of SPME to such properties.

AB - In order to explore the analytical performance of Headspace-Solid-phase Microextraction (HS-SPME), the sensitivity of gas chromatography (GC)-Mass Spectrometry (MS) determinations was examined in terms of calibration slopes, that is, response factor values of selected volatile organic compounds (VOC). The HS-SPME was applied to extract two kinds of gaseous VOC analytes, namely group I (methyl ethyl ketone, isobutyl alcohol, methyl isobutyl ketone, and butyl acetate, all having high water solubility) and group II (benzene, toluene, styrene, and xylene, all having moderate water solubility) from water solutions. The results, derived by both external and internal calibration, were then evaluated by considering headspace sample volume and solute volatility. In the case of solutes consisting of group I, sensitivity seems to increase with increasing HS size, although there are no such discernible patterns for group II solutes. The observed relative patterns in extraction efficiency may be accounted for by the differences in intermolecular forces present between the compounds of groups I and II and the possible effects of diffusion kinetics of the VOCs to the SPME fiber or competitive adsorption between different VOCs. As such, sensitivity of HS-SPME is tightly affected by the air-water partitioning properties of the target compounds and the response of SPME to such properties.

KW - Environmental air samples

KW - Gas chromatography with mass spectrometry

KW - Odorants

KW - Solid phase microextraction

KW - Volatile organic compounds

UR - http://www.scopus.com/inward/record.url?scp=80053550193&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=80053550193&partnerID=8YFLogxK

U2 - 10.1080/00032719.2011.551854

DO - 10.1080/00032719.2011.551854

M3 - Article

AN - SCOPUS:80053550193

VL - 44

SP - 2457

EP - 2465

JO - Analytical Letters

JF - Analytical Letters

SN - 0003-2719

IS - 15

ER -