The symptom frequency characteristics of the hamilton depression rating scale and possible symptom clusters of depressive disorders in Korea

The CRESCEND study

Sae Heon Jang, Young Nam Park, Young Myo Jae, Tae Youn Jun, Min-Soo Lee, Jae Min Kim, Seung Hee Jeong, Jung Bum Kim

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Objective This study analyzed the symptom frequencies of 17-item Hamilton Depression Rating Scale (HDRS-17) to understand the characteristics of each item and to propose the possible symptoms clusters. Methods From psychiatric clinics of 18 Hospitals in Korea, 1,183 patients, diagnosed with major depressive disorder (psychotic or non-psychotic), dysthymia or depressive disorder not otherwise specified. according to DSM-IV criteria, participated in this study from January 2006 to August 2008. The frequencies of each item of HDRS-17 were analyzed according to sex and severity. In addition, we compared this study with a previous study performed in England by Hamilton and with two studies performed in Korea by Kim et al. Results The frequencies of HDRS-17 items varied widely in this study, ranging from 95.8% in work and activities to 37.4% in loss of weight. But, depressed mood, psychic anxiety and work and activities items exhibited constant and higher frequency or rank regardless of study, the severity of depression or sex. Insomnia early, somatic gastrointestinal, genital symptoms and insight showed relatively constant but lower frequency or rank in disregard of studies or the clinical variables. Other symptoms had variable frequencies or ranks according to the variable clinical situations (culture, time, sex, severity of depression). Conclusion We propose three clusters of symptoms in depressive disorders: core symptoms cluster, an associated symptoms, and a situation-specific symptoms. We can use these possible symptom clusters of depression in simplifying diagnosis of depression, increasing diagnostic specificity in special situation and indexing disease severity.

Original languageEnglish
Pages (from-to)312-319
Number of pages8
JournalPsychiatry Investigation
Volume8
Issue number4
DOIs
Publication statusPublished - 2011 Dec 1

Fingerprint

Korea
Depressive Disorder
Depression
Major Depressive Disorder
Sleep Initiation and Maintenance Disorders
Diagnostic and Statistical Manual of Mental Disorders
England
Psychiatry
Weight Loss
Anxiety

Keywords

  • Associate symptoms cluster
  • Core symptoms cluster
  • HDRS-17
  • Situation-specific symptoms cluster
  • Symptom frequency
  • Variation

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Biological Psychiatry

Cite this

The symptom frequency characteristics of the hamilton depression rating scale and possible symptom clusters of depressive disorders in Korea : The CRESCEND study. / Jang, Sae Heon; Park, Young Nam; Jae, Young Myo; Jun, Tae Youn; Lee, Min-Soo; Kim, Jae Min; Jeong, Seung Hee; Kim, Jung Bum.

In: Psychiatry Investigation, Vol. 8, No. 4, 01.12.2011, p. 312-319.

Research output: Contribution to journalArticle

Jang, Sae Heon ; Park, Young Nam ; Jae, Young Myo ; Jun, Tae Youn ; Lee, Min-Soo ; Kim, Jae Min ; Jeong, Seung Hee ; Kim, Jung Bum. / The symptom frequency characteristics of the hamilton depression rating scale and possible symptom clusters of depressive disorders in Korea : The CRESCEND study. In: Psychiatry Investigation. 2011 ; Vol. 8, No. 4. pp. 312-319.
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