The synchronization within and interaction between the default and dorsal attention networks in early infancy

Wei Gao, John H. Gilmore, Dinggang Shen, Jeffery Keith Smith, Hongtu Zhu, Weili Lin

Research output: Contribution to journalArticle

76 Citations (Scopus)

Abstract

An anticorrelated interaction between the dorsal attention and the default-mode networks has been observed, although how these 2 networks establish such relationship remains elusive. Behavioral studies have reported the emergence of attention and default network-related functions and a preliminary competing relationship between them at early infancy. This study attempted to test the hypothesis - resting-state functional magnetic resonance imaging will demonstrate not only improved network synchronization of the dorsal attention and the default networks, respectively, during the first 2 years of life but also an anticorrelated network interaction pattern between the 2 networks at 1 year which will be further enhanced at 2 years old. Our results demonstrate that both networks start from an isolated region in neonates but evolve to highly synchronized networks at 1 year old. Paralleling the individual network maturation process, the anticorrelated behaviors are absent at birth but become apparent at 1 year and are further enhanced during the second year of life. Our studies elucidate not only the individual maturation process of the dorsal attention and default networks but also offer evidence that the maturation of the individual networks may be needed prior exhibiting the adult-like interaction patterns between the 2 networks.

Original languageEnglish
Pages (from-to)594-603
Number of pages10
JournalCerebral Cortex
Volume23
Issue number3
DOIs
Publication statusPublished - 2013 Feb 18
Externally publishedYes

Fingerprint

Magnetic Resonance Imaging
Parturition

Keywords

  • anticorrelation
  • brain development
  • fMRI
  • functional connectivity
  • resting state

ASJC Scopus subject areas

  • Cognitive Neuroscience
  • Cellular and Molecular Neuroscience

Cite this

The synchronization within and interaction between the default and dorsal attention networks in early infancy. / Gao, Wei; Gilmore, John H.; Shen, Dinggang; Smith, Jeffery Keith; Zhu, Hongtu; Lin, Weili.

In: Cerebral Cortex, Vol. 23, No. 3, 18.02.2013, p. 594-603.

Research output: Contribution to journalArticle

Gao, Wei ; Gilmore, John H. ; Shen, Dinggang ; Smith, Jeffery Keith ; Zhu, Hongtu ; Lin, Weili. / The synchronization within and interaction between the default and dorsal attention networks in early infancy. In: Cerebral Cortex. 2013 ; Vol. 23, No. 3. pp. 594-603.
@article{4bb04c54960c4c6f83832a1a5277826b,
title = "The synchronization within and interaction between the default and dorsal attention networks in early infancy",
abstract = "An anticorrelated interaction between the dorsal attention and the default-mode networks has been observed, although how these 2 networks establish such relationship remains elusive. Behavioral studies have reported the emergence of attention and default network-related functions and a preliminary competing relationship between them at early infancy. This study attempted to test the hypothesis - resting-state functional magnetic resonance imaging will demonstrate not only improved network synchronization of the dorsal attention and the default networks, respectively, during the first 2 years of life but also an anticorrelated network interaction pattern between the 2 networks at 1 year which will be further enhanced at 2 years old. Our results demonstrate that both networks start from an isolated region in neonates but evolve to highly synchronized networks at 1 year old. Paralleling the individual network maturation process, the anticorrelated behaviors are absent at birth but become apparent at 1 year and are further enhanced during the second year of life. Our studies elucidate not only the individual maturation process of the dorsal attention and default networks but also offer evidence that the maturation of the individual networks may be needed prior exhibiting the adult-like interaction patterns between the 2 networks.",
keywords = "anticorrelation, brain development, fMRI, functional connectivity, resting state",
author = "Wei Gao and Gilmore, {John H.} and Dinggang Shen and Smith, {Jeffery Keith} and Hongtu Zhu and Weili Lin",
year = "2013",
month = "2",
day = "18",
doi = "10.1093/cercor/bhs043",
language = "English",
volume = "23",
pages = "594--603",
journal = "Cerebral Cortex",
issn = "1047-3211",
publisher = "Oxford University Press",
number = "3",

}

TY - JOUR

T1 - The synchronization within and interaction between the default and dorsal attention networks in early infancy

AU - Gao, Wei

AU - Gilmore, John H.

AU - Shen, Dinggang

AU - Smith, Jeffery Keith

AU - Zhu, Hongtu

AU - Lin, Weili

PY - 2013/2/18

Y1 - 2013/2/18

N2 - An anticorrelated interaction between the dorsal attention and the default-mode networks has been observed, although how these 2 networks establish such relationship remains elusive. Behavioral studies have reported the emergence of attention and default network-related functions and a preliminary competing relationship between them at early infancy. This study attempted to test the hypothesis - resting-state functional magnetic resonance imaging will demonstrate not only improved network synchronization of the dorsal attention and the default networks, respectively, during the first 2 years of life but also an anticorrelated network interaction pattern between the 2 networks at 1 year which will be further enhanced at 2 years old. Our results demonstrate that both networks start from an isolated region in neonates but evolve to highly synchronized networks at 1 year old. Paralleling the individual network maturation process, the anticorrelated behaviors are absent at birth but become apparent at 1 year and are further enhanced during the second year of life. Our studies elucidate not only the individual maturation process of the dorsal attention and default networks but also offer evidence that the maturation of the individual networks may be needed prior exhibiting the adult-like interaction patterns between the 2 networks.

AB - An anticorrelated interaction between the dorsal attention and the default-mode networks has been observed, although how these 2 networks establish such relationship remains elusive. Behavioral studies have reported the emergence of attention and default network-related functions and a preliminary competing relationship between them at early infancy. This study attempted to test the hypothesis - resting-state functional magnetic resonance imaging will demonstrate not only improved network synchronization of the dorsal attention and the default networks, respectively, during the first 2 years of life but also an anticorrelated network interaction pattern between the 2 networks at 1 year which will be further enhanced at 2 years old. Our results demonstrate that both networks start from an isolated region in neonates but evolve to highly synchronized networks at 1 year old. Paralleling the individual network maturation process, the anticorrelated behaviors are absent at birth but become apparent at 1 year and are further enhanced during the second year of life. Our studies elucidate not only the individual maturation process of the dorsal attention and default networks but also offer evidence that the maturation of the individual networks may be needed prior exhibiting the adult-like interaction patterns between the 2 networks.

KW - anticorrelation

KW - brain development

KW - fMRI

KW - functional connectivity

KW - resting state

UR - http://www.scopus.com/inward/record.url?scp=84873682321&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84873682321&partnerID=8YFLogxK

U2 - 10.1093/cercor/bhs043

DO - 10.1093/cercor/bhs043

M3 - Article

C2 - 22368080

AN - SCOPUS:84873682321

VL - 23

SP - 594

EP - 603

JO - Cerebral Cortex

JF - Cerebral Cortex

SN - 1047-3211

IS - 3

ER -