Theranostic applications of organic nanoparticles for cancer treatment

Ji Young Yhee, Sohee Son, Namho Kim, Kuiwon Choi, Ick Chan Kwon

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Research in nanotechnology-based molecular imaging and targeted drug delivery has resulted in a noticeable progress in cancer theranosis, the simultaneous application of cancer therapy and diagnosis. Theranostic nanoparticles (NPs) have been developed using diverse base materials, and organic materials are of major interest in the synthesis and preparation of these NPs. A variety of organic NPs have their own advantages, depending on the physiochemical and biological properties of the base materials. This article reviews recent developments in organic NPs, which are grouped into four major kinds of base materials: lipids, polysaccharides, peptides/proteins, and synthetic polymers. The advantageous properties of frequently used base materials and practical performance of the various organic NPs in vivo are discussed. These theranostic NPs offer new opportunities for effective cancer treatment.

Original languageEnglish
Pages (from-to)239-249
Number of pages11
JournalMRS Bulletin
Volume39
Issue number3
DOIs
Publication statusPublished - 2014 Mar 1
Externally publishedYes

Keywords

  • Biomaterial
  • Biomedical
  • Nanostructure
  • Organic
  • Polymer

ASJC Scopus subject areas

  • Materials Science(all)
  • Condensed Matter Physics
  • Physical and Theoretical Chemistry

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  • Cite this

    Yhee, J. Y., Son, S., Kim, N., Choi, K., & Kwon, I. C. (2014). Theranostic applications of organic nanoparticles for cancer treatment. MRS Bulletin, 39(3), 239-249. https://doi.org/10.1557/mrs.2014.30