Thinking Inside the Box: Endogenous α-Anomeric Lipid Antigens

Jessica Kim, Ji Hyung Kim, Florian Winau

Research output: Contribution to journalShort survey

5 Citations (Scopus)

Abstract

The most powerful iNKT cell antigen is α-galactosylceramide (α-GalCer), derived from the marine sponge. However, α-anomeric glycolipids are thought to be absent in mammals. In this issue of Immunity, Kain etal., (2014) demonstrate the presence of mammalian α-linked glycosylceramides, such as α-GalCer. The most powerful iNKT cell antigen is α-galactosylceramide (α-GalCer), derived from the marine sponge. However, α-anomeric glycolipids are thought to be absent in mammals. In this issue of Immunity, Kain etal. demonstrate the presence of mammalian α-linked glycosylceramides, such as α-GalCer.

Original languageEnglish
Pages (from-to)505-506
Number of pages2
JournalImmunity
Volume41
Issue number4
DOIs
Publication statusPublished - 2014 Oct 16
Externally publishedYes

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology
  • Infectious Diseases

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