Thottapalayam virus, a prototype shrewborne hantavirus

Jin Won Song, Luck J. Baek, Connie S. Schmaljohn, Richard Yanagihara

Research output: Contribution to journalArticle

70 Citations (Scopus)

Abstract

Thottapalayam virus (TPMV) has been placed in the genus Hantavirus of the family Bunyaviridae by virtue of its morphologic features and overall genetic similarities to well-characterized rodentborne hantaviruses. This virus has been isolated from the Asian house shrew (Suncus murinus); however, whether TPMV is naturally harbored by an insectivore host or represents spillover from a rodent reservoir host is unknown. Our analysis of published and unpublished data on the experimental host range, genetics, and molecular phylogeny of TPMV supports coevolution of TPMV with its nonrodent reservoir host. Future studies on the epizootiology of TPMV and investigations of new shrewborne hantaviruses will provide additional insights into the evolutionary origin of hantaviruses in their rodent and insectivore reservoir hosts. Such investigations may also provide clues about determinants of hantavirus pathogenicity and virulence.

Original languageEnglish
Pages (from-to)980-985
Number of pages6
JournalEmerging Infectious Diseases
Volume13
Issue number7
Publication statusPublished - 2007 Jul 1

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Hantavirus
Viruses
Virulence
Rodentia
Bunyaviridae
Shrews
Host Specificity
Phylogeny
Molecular Biology

ASJC Scopus subject areas

  • Microbiology (medical)

Cite this

Song, J. W., Baek, L. J., Schmaljohn, C. S., & Yanagihara, R. (2007). Thottapalayam virus, a prototype shrewborne hantavirus. Emerging Infectious Diseases, 13(7), 980-985.

Thottapalayam virus, a prototype shrewborne hantavirus. / Song, Jin Won; Baek, Luck J.; Schmaljohn, Connie S.; Yanagihara, Richard.

In: Emerging Infectious Diseases, Vol. 13, No. 7, 01.07.2007, p. 980-985.

Research output: Contribution to journalArticle

Song, JW, Baek, LJ, Schmaljohn, CS & Yanagihara, R 2007, 'Thottapalayam virus, a prototype shrewborne hantavirus', Emerging Infectious Diseases, vol. 13, no. 7, pp. 980-985.
Song JW, Baek LJ, Schmaljohn CS, Yanagihara R. Thottapalayam virus, a prototype shrewborne hantavirus. Emerging Infectious Diseases. 2007 Jul 1;13(7):980-985.
Song, Jin Won ; Baek, Luck J. ; Schmaljohn, Connie S. ; Yanagihara, Richard. / Thottapalayam virus, a prototype shrewborne hantavirus. In: Emerging Infectious Diseases. 2007 ; Vol. 13, No. 7. pp. 980-985.
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