Three New Chalcones from the Aerial Parts of Angelica keiskei

Yun Seo Kil, Jaeyoung Kwon, Dongho Lee, Eun Kyoung Seo

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Three new chalcones, 3′-carboxymethyl-4,2′-dihydroxy-4′-methoxychalcone (1), (±)-4,2′,4′-trihydroxy-3′-[(3-hydroxy-2,2-dimethyl-6-methylenecyclohexyl)methyl]chalcone (2), and 2′′-hydroxyangelichalcone (3), were isolated from the aerial parts of Angelica keiskei (Umbelliferae) together with five known compounds, artocarmitin A (4), (+)-cis-(3′R,4′R)-methylkhellactone (5), (-)-trans-(3′R,4′S)-methylkhellactone (6), 3,4-dihydroxanthotoxin (7), and (Z)-p-coumaryl alcohol (8). The known compounds 4 - 8 were identified from A. keiskei for the first time. The structures of 1 - 3 were elucidated by interpreting spectroscopic data including 1D- and 2D-NMR.

Original languageEnglish
Pages (from-to)393-397
Number of pages5
JournalHelvetica Chimica Acta
Volume99
Issue number5
DOIs
Publication statusPublished - 2016 May 1

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Keywords

  • Angelica keiskei
  • Chalcones
  • Flavonoids
  • Phenolic compounds
  • Umbelliferae

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Catalysis
  • Drug Discovery
  • Physical and Theoretical Chemistry
  • Inorganic Chemistry

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