Ti scaffolds with tailored porosities and mechanical properties using porous polymer templates

Jung Bin Lee, Min Kyung Ahn, Young-Hag Koh, Hyun Lee, Hyoun Ee Kim

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

This study proposes a simple, useful approach to produce three-dimensionally macrochanneled titanium (Ti) scaffolds with tailored porosities and mechanical properties using porous polylactic acid (PLA) templates that can be prepared by conventional solid freeform fabrication (SFF) technique. Specifically, methylcellulose (MC) polymer was used as a binder since it could effectively bind coarse Ti particles and remain chemically stable inert in organic solvents used to dissolve PLA polymer. A Ti slurry-filled PLA was immersed in chloroform to remove the PLA template, followed by sintering at 1300 °C for 3 h in a vacuum. The use of a relatively small amount of a MC binder and removal of the PLA template in solvent enabled the construction of straight Ti frameworks and macrochannels in a 3-D periodic pattern without severe impurity contamination. This tightly controlled porous structure enabled the achievement of high compressive strengths without a catastrophic failure, while the compressive strength increased from ~. 72 MPa to 121 MPa with a decrease in overall porosity from ~. 75 vol% to ~. 67 vol%. In addition, the porous Ti scaffolds showed good biocompatibility, which was assessed by in vitro cell tests in terms of attachment, proliferation, and differentiation of MC3T3-E1 cells.

Original languageEnglish
Pages (from-to)323-331
Number of pages9
JournalMaterials and Design
Volume101
DOIs
Publication statusPublished - 2016 Jul 5

Fingerprint

Titanium
Scaffolds
Polymers
Porosity
Mechanical properties
Acids
Methylcellulose
Compressive strength
Binders
Layered manufacturing
Scaffolds (biology)
Chloroform
Chlorine compounds
Biocompatibility
Organic solvents
Contamination
Sintering
poly(lactic acid)
Vacuum
Impurities

Keywords

  • Bone scaffold
  • Porous
  • Porous structure
  • Solid freeform fabrication

ASJC Scopus subject areas

  • Mechanical Engineering
  • Mechanics of Materials
  • Materials Science(all)

Cite this

Ti scaffolds with tailored porosities and mechanical properties using porous polymer templates. / Lee, Jung Bin; Ahn, Min Kyung; Koh, Young-Hag; Lee, Hyun; Kim, Hyoun Ee.

In: Materials and Design, Vol. 101, 05.07.2016, p. 323-331.

Research output: Contribution to journalArticle

Lee, Jung Bin ; Ahn, Min Kyung ; Koh, Young-Hag ; Lee, Hyun ; Kim, Hyoun Ee. / Ti scaffolds with tailored porosities and mechanical properties using porous polymer templates. In: Materials and Design. 2016 ; Vol. 101. pp. 323-331.
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